UniProt P55859
Purine nucleoside phosphorylase (P55859)
Purine nucleoside phosphorylase (UniProt P55859): 42 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P55859
- Protein
- Purine nucleoside phosphorylase
- Experimental structures
- 42
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
43 records of P55859 in the MolNFT archive: 42 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A9O | Bovine purine nucleoside phosphorylase complexed with phosphate | x-ray diffraction | A | — | — |
| 1A9O | Bovine purine nucleoside phosphorylase complexed with phosphate | x-ray diffraction | A | — | — |
| 1A9P | Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate | x-ray diffraction | A | — | — |
| 1A9P | Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate | x-ray diffraction | A | — | — |
| 1A9Q | Bovine purine nucleoside phosphorylase complexed with inosine | x-ray diffraction | A | — | — |
| 1A9Q | Bovine purine nucleoside phosphorylase complexed with inosine | x-ray diffraction | A | — | — |
| 1A9R | Bovine purine nucleoside phosphorylase complexed with hypoxanthine and sulfate | x-ray diffraction | A | — | — |
| 1A9R | Bovine purine nucleoside phosphorylase complexed with hypoxanthine and sulfate | x-ray diffraction | A | — | — |
| 1A9S | Bovine purine nucleoside phosphorylase complexed with inosine and sulfate | x-ray diffraction | A | — | — |
| 1A9S | Bovine purine nucleoside phosphorylase complexed with inosine and sulfate | x-ray diffraction | A | — | — |
| 1A9T | Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate | x-ray diffraction | A | — | — |
| 1A9T | Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate | x-ray diffraction | A | — | — |
| 1B8N | Purine nucleoside phosphorylase | x-ray diffraction | A | — | — |
| 1B8N | Purine nucleoside phosphorylase | x-ray diffraction | A | — | — |
| 1B8O | Purine nucleoside phosphorylase | x-ray diffraction | A | — | — |
| 1B8O | Purine nucleoside phosphorylase | x-ray diffraction | A | — | — |
| 1FXU | Purine nucleoside phosphorylase from calf spleen in complex with N(7)-acycloguanosine inhibitor and… | x-ray diffraction | A | — | — |
| 1FXU | Purine nucleoside phosphorylase from calf spleen in complex with N(7)- acycloguanosine inhibitor… | x-ray diffraction | A | — | — |
| 1LV8 | Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1LV8 | Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1LVU | Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1LVU | Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1PBN | Purine nucleoside phosphorylase | x-ray diffraction | A | — | — |
| 1PBN | Purine nucleoside phosphorylase | x-ray diffraction | A | — | — |
| 1V48 | Calf spleen purine nucleoside phosphorylase (PNP) binary complex with… | x-ray diffraction | A | — | — |
| 1V48 | Calf spleen purine nucleoside phosphorylase (pnp) binary complex with… | x-ray diffraction | A | — | — |
| 1VFN | Purine nucleoside phosphorylase | x-ray diffraction | A | — | — |
| 1VFN | Purine nucleoside phosphorylase | x-ray diffraction | A | — | — |
| 2AI1 | Purine nucleoside phosphorylase from calf spleen | x-ray diffraction | A | — | — |
| 2AI1 | Purine nucleoside phosphorylase from calf spleen | x-ray diffraction | A | — | — |
| 2AI2 | Purine nucleoside phosphorylase from calf spleen | x-ray diffraction | A | — | — |
| 2AI2 | Purine nucleoside phosphorylase from calf spleen | x-ray diffraction | A | — | — |
| 2AI3 | Purine nucleoside phosphorylase from calf spleen | x-ray diffraction | A | — | — |
| 2AI3 | Purine nucleoside phosphorylase from calf spleen | x-ray diffraction | A | — | — |
| 2QPL | Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine… | x-ray diffraction | A | — | — |
| 2QPL | Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine… | x-ray diffraction | A | — | — |
| 3FUC | Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue… | x-ray diffraction | A, B, C | — | — |
| 3FUC | Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue… | x-ray diffraction | A, B, C | — | — |
| 3PNP | The high resolution crystal structure of bovine spleen purine nucleoside phosphorylase in complex… | x-ray diffraction | A | — | — |
| 3PNP | The high resolution crystal structure of bovine spleen purine nucleoside phosphorylase in complex… | x-ray diffraction | A | — | — |
| 4PNP | The high resolution crystal structure of bovine spleen purine nucleoside phosphorylase in complex… | x-ray diffraction | A | — | — |
| 4PNP | The high resolution crystal structure of bovine spleen purine nucleoside phosphorylase in complex… | x-ray diffraction | A | — | — |
| P55859 | AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (P55859) | predicted | A | — | 2 (best 0.67) |
Experiment against prediction
- 1FXU chain A against the predicted model P55859: TM-score 1.00, RMSD 0.41 Å
- 1FXU chain A against the predicted model P55859: TM-score 1.00, RMSD 0.41 Å
- 1B8O chain A against the predicted model P55859: TM-score 0.99, RMSD 0.55 Å
- 1B8O chain A against the predicted model P55859: TM-score 0.99, RMSD 0.55 Å
- 2AI3 chain A against the predicted model P55859: TM-score 0.99, RMSD 0.61 Å
- 2AI3 chain A against the predicted model P55859: TM-score 0.99, RMSD 0.61 Å
- 1A9S chain A against the predicted model P55859: TM-score 0.99, RMSD 0.69 Å
- 1A9S chain A against the predicted model P55859: TM-score 0.99, RMSD 0.69 Å
- 1B8N chain A against the predicted model P55859: TM-score 0.99, RMSD 0.72 Å
- 1B8N chain A against the predicted model P55859: TM-score 0.99, RMSD 0.72 Å
Elsewhere
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