UniProt P49406
39S ribosomal protein L19, mitochondrial (P49406)
39S ribosomal protein L19, mitochondrial (UniProt P49406): 36 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P49406
- Protein
- 39S ribosomal protein L19, mitochondrial
- Experimental structures
- 36
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 16 · 7 records with a druggable one
Structures
37 records of P49406 in the MolNFT archive: 36 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J7Y | Structure of the large ribosomal subunit from human mitochondria | electron microscopy | Q | — | — |
| 3J7Y | Structure of the large ribosomal subunit from human mitochondria | electron microscopy | Q | — | — |
| 3J9M | Structure of the human mitochondrial ribosome (class 1) | electron microscopy | Q | — | — |
| 5OOL | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | Q | MG | — |
| 5OOL | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | Q | MG | — |
| 5OOM | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | Q | — | — |
| 5OOM | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | Q | — | — |
| 6I9R | Large subunit of the human mitochondrial ribosome in complex with Virginiamycin M and Quinupristin | electron microscopy | Q | MG | — |
| 6NU2 | Structural insights into unique features of the human mitochondrial ribosome recycling | electron microscopy | Q | — | — |
| 6VLZ | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) | electron microscopy | Q | MG | — |
| 6ZS9 | Human mitochondrial ribosome in complex with ribosome recycling factor | electron microscopy | XQ | MG | — |
| 6ZSB | Human mitochondrial ribosome in complex with mRNA and P-site tRNA | electron microscopy | XQ | MG | — |
| 6ZSC | Human mitochondrial ribosome in complex with E-site tRNA | electron microscopy | XQ | MG | 1 (best 0.86) |
| 7L20 | Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt. | electron microscopy | Q | — | — |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | Q | MG | 3 (best 0.87) |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | Q | — | — |
| 7OF4 | Structure of mature human mitochondrial ribosome large subunit in complex with GTPBP6 (PTC… | electron microscopy | Q | MG | — |
| 7OF5 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | Q | MG | 2 (best 0.87) |
| 7OI6 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 1 | electron microscopy | Q | — | — |
| 7OI7 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2 | electron microscopy | Q | MG | — |
| 7OI8 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3A | electron microscopy | Q | MG | — |
| 7OI9 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B | electron microscopy | Q | MG | — |
| 7OIA | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3C | electron microscopy | Q | MG | — |
| 7OIB | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3D | electron microscopy | Q | MG | — |
| 7OIC | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4 | electron microscopy | Q | MG | — |
| 7OIE | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5B | electron microscopy | Q | — | — |
| 7PD3 | Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and… | electron microscopy | Q | MG, U, A, C | — |
| 7QH6 | Cryo-EM structure of the human mtlsu assembly intermediate upon MRM2 depletion - class 1 | electron microscopy | Q | — | — |
| 7QH7 | Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4 | electron microscopy | Q | — | — |
| 7QH7 | Cryo-EM structure of the human mtlsu assembly intermediate upon MRM2 depletion - class 4 | electron microscopy | Q | — | — |
| 7QI6 | Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution | electron microscopy | Q | MG | — |
| 8K2A | Cryo-EM structure of the human 55S mitoribosome with Tigecycline | electron microscopy | LS | MG | 2 (best 0.86) |
| 8OIR | 55S human mitochondrial ribosome with mtRF1 and P-site tRNA | electron microscopy | BX | MG | 1 (best 0.86) |
| 8OIS | 28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | BX | — | — |
| 8OIT | 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | BX | MG | 1 (best 0.86) |
| 8PK0 | human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7 | electron microscopy | Q | MG | 1 (best 0.83) |
| P49406 | AlphaFold monomer V2.0 prediction for 39S ribosomal protein L19, mitochondrial (P49406) | predicted | A | — | 5 (best 0.47) |
Ligands
Experiment against prediction
- 3J9M chain Q against the predicted model P49406: TM-score 0.99, RMSD 0.54 Å
- 7OF4 chain Q against the predicted model P49406: TM-score 0.99, RMSD 0.54 Å
- 8K2A chain LS against the predicted model P49406: TM-score 0.99, RMSD 0.55 Å
- 7L20 chain Q against the predicted model P49406: TM-score 0.99, RMSD 0.56 Å
- 3J7Y chain Q against the predicted model P49406: TM-score 0.99, RMSD 0.55 Å
- 3J7Y chain Q against the predicted model P49406: TM-score 0.99, RMSD 0.55 Å
- 6NU2 chain Q against the predicted model P49406: TM-score 0.99, RMSD 0.59 Å
- 6I9R chain Q against the predicted model P49406: TM-score 0.98, RMSD 0.75 Å
- 5OOM chain Q against the predicted model P49406: TM-score 0.98, RMSD 0.94 Å
- 5OOM chain Q against the predicted model P49406: TM-score 0.98, RMSD 0.94 Å
Elsewhere
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