MolNFT v1 · #379172 · protein
AlphaFold monomer V2.0 prediction for 39S ribosomal protein L19, mitochondrial (P49406)
P49406: “AlphaFold monomer V2.0 prediction for 39S ribosomal protein L19, mitochondrial (P49406)”. 5 pockets (best druggability 0.47). MolNFT v1 #379172 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49406
- Type
- protein
- Length
- 292 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
- Molecule
- 39S ribosomal protein L19, mitochondrial
- UniProt
- P49406
- Pockets
- 5 · best druggability 0.47
Structure
1 distinct chain · 23% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 39S ribosomal protein L19, mitochondrial | protein | 292 | 23% helix, 17% strand | P49406 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 209 | 0.47 | 0.74 | 29 | empty |
| 2 | 142 | 0.43 | 0.75 | 16 | empty |
| 3 | 128 | 0.40 | 0.75 | 24 | empty |
| 4 | 64 | 0.35 | 0.77 | 22 | empty |
| 5 | 90 | 0.31 | 0.73 | 17 | empty |
Compared structures
- 8OIT · 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA · an experimental structure of the same protein · chain A against BX, TM-score 0.75
- 8OIR · 55S human mitochondrial ribosome with mtRF1 and P-site tRNA · an experimental structure of the same protein · chain A against BX, TM-score 0.75
- 7QI6 · Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution · an experimental structure of the same protein · chain A against Q, TM-score 0.75
- 6VLZ · Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) · an experimental structure of the same protein · chain A against Q, TM-score 0.75
- 6ZSC · Human mitochondrial ribosome in complex with E-site tRNA · an experimental structure of the same protein · chain A against XQ, TM-score 0.75
- 6ZS9 · Human mitochondrial ribosome in complex with ribosome recycling factor · an experimental structure of the same protein · chain A against XQ, TM-score 0.75
- 7L20 · Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and… · an experimental structure of the same protein · chain A against Q, TM-score 0.75
- 6ZSB · Human mitochondrial ribosome in complex with mRNA and P-site tRNA · an experimental structure of the same protein · chain A against XQ, TM-score 0.75
- 7ODT · State C of the human mitoribosomal large subunit assembly intermediate · an experimental structure of the same protein · chain A against Q, TM-score 0.75
- 8PK0 · human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7 · an experimental structure of the same protein · chain A against Q, TM-score 0.75
- 3J9M · Structure of the human mitochondrial ribosome (class 1) · an experimental structure of the same protein · chain A against Q, TM-score 0.74
- 8K2A · Cryo-EM structure of the human 55S mitoribosome with Tigecycline · an experimental structure of the same protein · chain A against LS, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49406
- Elsewhere: UniProt P49406 · AlphaFold DB P49406
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