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AlphaFold monomer V2.0 prediction for 39S ribosomal protein L19, mitochondrial (P49406)

Analyse AlphaFold monomer V2.0 prediction for 39S ribosomal protein L19, mitochondrial… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P49406
Type
protein
Length
292 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xd1A2963012bEcbC7A8f505464439Ab678C48936f
Molecule
39S ribosomal protein L19, mitochondrial
UniProt
P49406
Pockets
5 · best druggability 0.47

Structure

1 distinct chain · 23% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A39S ribosomal protein L19, mitochondrialprotein29223% helix, 17% strandP49406

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12090.470.7429empty
21420.430.7516empty
31280.400.7524empty
4640.350.7722empty
5900.310.7317empty

Compared structures

  • 6ZM6 · Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA · an experimental structure of the same protein · chain A against Q, TM-score 0.76
  • 6ZM5 · Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent… · an experimental structure of the same protein · chain A against Q, TM-score 0.76
  • 7QI4 · Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA) · an experimental structure of the same protein · chain A against Q, TM-score 0.76
  • 7QI5 · Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A… · an experimental structure of the same protein · chain A against Q, TM-score 0.75
  • 8ANY · Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs… · an experimental structure of the same protein · chain A against Q, TM-score 0.75
  • 8OIT · 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA · an experimental structure of the same protein · chain A against BX, TM-score 0.75
  • 8OIR · 55S human mitochondrial ribosome with mtRF1 and P-site tRNA · an experimental structure of the same protein · chain A against BX, TM-score 0.75
  • 7QI6 · Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution · an experimental structure of the same protein · chain A against Q, TM-score 0.75
  • 6VMI · Structure of the human mitochondrial ribosome-EF-G1 complex (ClassIII) · an experimental structure of the same protein · chain A against Q, TM-score 0.75
  • 6VLZ · Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) · an experimental structure of the same protein · chain A against Q, TM-score 0.75
  • 6ZSC · Human mitochondrial ribosome in complex with E-site tRNA · an experimental structure of the same protein · chain A against XQ, TM-score 0.75
  • 7L08 · Cryo-EM structure of the human 55S mitoribosome-RRFmt complex. · an experimental structure of the same protein · chain A against Q, TM-score 0.75

Analyse

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