UniProt P32349
DNA-directed RNA polymerase III subunit RPC3 (P32349)
DNA-directed RNA polymerase III subunit RPC3 (UniProt P32349): 31 experimental structures and 1 predicted model on GenesisL1, 62 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32349
- Protein
- DNA-directed RNA polymerase III subunit RPC3
- Experimental structures
- 31
- Predicted models
- 1
- Pockets
- 62 · 13 records with a druggable one
Structures
32 records of P32349 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FJ8 | Cryo-EM structure of yeast RNA polymerase III elongation complex at 3. 9 A | electron microscopy | O | — | — |
| 5FJ8 | Cryo-EM structure of yeast RNA polymerase III elongation complex at 3. 9 a | electron microscopy | O | — | — |
| 5FJ9 | Cryo-EM structure of yeast apo RNA polymerase III at 4.6 A | electron microscopy | O | — | — |
| 5FJ9 | Cryo-EM structure of yeast apo RNA polymerase III at 4.6 a | electron microscopy | O | — | — |
| 5FJA | Cryo-EM structure of yeast RNA polymerase III at 4.7 A | electron microscopy | O | — | 5 (best 0.84) |
| 5FJA | Cryo-EM structure of yeast RNA polymerase III at 4.7 a | electron microscopy | O | — | — |
| 6CNB | Yeast RNA polymerase III initial transcribing complex | electron microscopy | O | — | — |
| 6CNC | Yeast RNA polymerase III open complex | electron microscopy | O | — | — |
| 6CND | Yeast RNA polymerase III natural open complex (noc) | electron microscopy | O | — | — |
| 6CNF | Yeast RNA polymerase III elongation complex | electron microscopy | O | — | — |
| 6EU0 | RNA polymerase III open pre-initiation complex (oc-pic) | electron microscopy | O | — | — |
| 6EU1 | RNA Polymerase III - open DNA complex (OC-POL3). | electron microscopy | O | — | — |
| 6EU1 | RNA polymerase III - open DNA complex (oc-POL3). | electron microscopy | O | — | — |
| 6EU2 | Apo RNA polymerase III - open conformation (OPOL3) | electron microscopy | O | — | — |
| 6EU3 | Apo RNA polymerase III - closed conformation (CPOL3) | electron microscopy | O | — | — |
| 6F40 | RNA polymerase III open complex | electron microscopy | O | — | — |
| 6F41 | RNA Polymerase III initially transcribing complex | electron microscopy | O | — | 3 (best 0.86) |
| 6F41 | RNA polymerase III initially transcribing complex | electron microscopy | O | — | — |
| 6F42 | RNA Polymerase III closed complex CC1. | electron microscopy | O | — | 3 (best 0.86) |
| 6F42 | RNA polymerase III closed complex CC1. | electron microscopy | O | — | — |
| 6F44 | RNA Polymerase III closed complex CC2. | electron microscopy | O | — | 2 (best 0.84) |
| 6F44 | RNA polymerase III closed complex CC2. | electron microscopy | O | — | — |
| 6TUT | Cryo-EM structure of the RNA Polymerase III-Maf1 complex | electron microscopy | O | — | 6 (best 0.87) |
| 6TUT | Cryo-EM structure of the RNA polymerase III-MAF1 complex | electron microscopy | O | — | — |
| 7Z1L | Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC) | electron microscopy | O | — | 4 (best 0.86) |
| 7Z1M | Structure of yeast RNA Polymerase III Elongation Complex (EC) | electron microscopy | O | — | 5 (best 0.86) |
| 7Z1N | Structure of yeast RNA Polymerase III Delta C53-C37-C11 | electron microscopy | O | — | 7 (best 0.87) |
| 7Z1N | Structure of yeast RNA polymerase III delta C53-C37-C11 | electron microscopy | O | — | 7 (best 0.87) |
| 7Z1O | Structure of yeast RNA Polymerase III PTC + NTPs | electron microscopy | O | — | 5 (best 0.86) |
| 7Z2Z | Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A | electron microscopy | O | — | 2 (best 0.86) |
| 8BWS | Structure of yeast RNA Polymerase III elongation complex at 3.3 A | electron microscopy | O | — | 4 (best 0.85) |
| P32349 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC3 (P32349) | predicted | A | — | 9 (best 0.79) |
Experiment against prediction
- 6TUT chain O against the predicted model P32349: TM-score 0.97, RMSD 1.63 Å
- 6TUT chain O against the predicted model P32349: TM-score 0.97, RMSD 1.63 Å
- 7Z1O chain O against the predicted model P32349: TM-score 0.97, RMSD 1.85 Å
- 7Z1L chain O against the predicted model P32349: TM-score 0.97, RMSD 1.91 Å
- 8BWS chain O against the predicted model P32349: TM-score 0.97, RMSD 1.91 Å
- 7Z1M chain O against the predicted model P32349: TM-score 0.96, RMSD 1.94 Å
- 7Z1N chain O against the predicted model P32349: TM-score 0.96, RMSD 1.84 Å
- 7Z1N chain O against the predicted model P32349: TM-score 0.96, RMSD 1.84 Å
- 7Z2Z chain O against the predicted model P32349: TM-score 0.96, RMSD 2.01 Å
- 6F40 chain O against the predicted model P32349: TM-score 0.96, RMSD 1.77 Å
Elsewhere
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