UniProt P22887
Nucleoside diphosphate kinase, cytosolic (P22887)
Nucleoside diphosphate kinase, cytosolic (UniProt P22887): 50 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P22887
- Protein
- Nucleoside diphosphate kinase, cytosolic
- Experimental structures
- 50
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
51 records of P22887 in the MolNFT archive: 50 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B4S | Structure of nucleoside diphosphate kinase H122G mutant | x-ray diffraction | A, B, C | — | — |
| 1B4S | Structure of nucleoside diphosphate kinase H122G mutant | x-ray diffraction | A, B, C | — | — |
| 1B99 | 3'-fluoro-uridine diphosphate binding to nucleoside diphosphate kinase | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1B99 | 3'-fluoro-uridine diphosphate binding to nucleoside diphosphate kinase | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1BUX | 3'-phosphorylated nucleotides binding to nucleoside diphosphate kinase | x-ray diffraction | A, B, C | — | — |
| 1BUX | 3'-phosphorylated nucleotides binding to nucleoside diphosphate kinase | x-ray diffraction | A, B, C | — | — |
| 1F3F | Structure of the H122G nucleoside diphosphate kinase / D4T-TRIPHOSPHATE.MG complex | x-ray diffraction | A, B, C | — | — |
| 1F3F | Structure of the H122G nucleoside diphosphate kinase / D4T- TRIPHOSPHATE.MG complex | x-ray diffraction | A, B, C | — | — |
| 1F6T | Structure of the nucleoside diphosphate KINASE/ALPHA-BORANO(RP)-TDP.MG complex | x-ray diffraction | A, B, C | — | — |
| 1F6T | Structure of the nucleoside diphosphate KINASE/ALPHA-BORANO(RP)-TDP.MG complex | x-ray diffraction | A, B, C | — | — |
| 1HHQ | Role of active site resiude Lys16 in Nucleoside Diphosphate Kinase | x-ray diffraction | A | — | — |
| 1HHQ | Role of active site resiude LYS16 in nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 1HIY | Binding of nucleotides to NDP kinase | x-ray diffraction | A, B, C | — | — |
| 1HIY | Binding of nucleotides to ndp kinase | x-ray diffraction | A, B, C | — | — |
| 1HLW | Structure of the H122A mutant of the nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 1HLW | Structure of the H122A mutant of the nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 1KDN | Structure of nucleoside diphosphate kinase | x-ray diffraction | A, B, C | — | — |
| 1KDN | Structure of nucleoside diphosphate kinase | x-ray diffraction | A, B, C | — | — |
| 1LEO | P100S nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 1LEO | P100S nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 1LWX | Azt diphosphate binding to nucleoside diphosphate kinase | x-ray diffraction | A, B, C | — | — |
| 1LWX | Azt diphosphate binding to nucleoside diphosphate kinase | x-ray diffraction | A, B, C | — | — |
| 1MN7 | NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP | x-ray diffraction | A, B | — | — |
| 1MN7 | Ndp kinase mutant (H122G;N119S;F64W) in complex with abazttp | x-ray diffraction | A, B | — | — |
| 1MN9 | NDP kinase mutant (H122G) complex with RTP | x-ray diffraction | A, B, C | — | — |
| 1MN9 | Ndp kinase mutant (H122G) complex with rtp | x-ray diffraction | A, B, C | — | — |
| 1NCL | Thermal stability of hexameric and tetrameric nucleoside, diphosphate kinases | x-ray diffraction | A | — | — |
| 1NCL | Thermal stability of hexameric and tetrameric nucleoside, diphosphate kinases | x-ray diffraction | A | — | — |
| 1NDC | X-ray structure of nucleoside diphosphate kinase complexed with dtdp and MG2+ at 2 a resolution | x-ray diffraction | A | — | — |
| 1NDC | X-ray structure of nucleoside diphosphate kinase complexed with dtdp and MG2+ at 2 a resolution | x-ray diffraction | A | — | — |
| 1NDK | X-ray structure of nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 1NDK | X-ray structure of nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 1NDP | Adenosine 5'-diphosphate binding and the active site of nucleoside diphosphate kinase | x-ray diffraction | A, B | — | — |
| 1NDP | Adenosine 5'-diphosphate binding and the active site of nucleoside diphosphate kinase | x-ray diffraction | A, B | — | — |
| 1NPK | Refined X-ray structure of dictyostelium nucleoside diphosphate kinase at 1,8 ångströms resolution | x-ray diffraction | A | — | — |
| 1NPK | Refined X-ray structure of dictyostelium nucleoside diphosphate kinase at 1,8 ångströms resolution | x-ray diffraction | A | — | — |
| 1NSP | Mechanism of phosphate transfer by nucleoside diphosphate kinase: X-ray structures of a… | x-ray diffraction | A | — | — |
| 1NSP | Mechanism of phosphate transfer by nucleoside diphosphate kinase: X- ray structures of a… | x-ray diffraction | A | — | — |
| 1PAE | nucleoside diphosphate kinase | x-ray diffraction | X | — | — |
| 1PAE | Nucleoside diphosphate kinase | x-ray diffraction | X | — | — |
| 1S5Z | NDP kinase in complex with adenosine phosphonoacetic acid | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1S5Z | Ndp kinase in complex with adenosine phosphonoacetic acid | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2BEF | Crystal structure of ndp kinase complexed with mg, ADP, and BEF3 | x-ray diffraction | A, B, C | — | — |
| 2BEF | Crystal structure of ndp kinase complexed with mg, ADP, and BEF3 | x-ray diffraction | A, B, C | — | — |
| 3FKB | Structure of NDPK H122G and tenofovir-diphosphate | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3FKB | Structure of ndpk H122G and tenofovir-diphosphate | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4C6A | High Resolution Structure of the Nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 4C6A | High resolution structure of the nucleoside diphosphate kinase | x-ray diffraction | A | — | — |
| 4CP5 | ndpK in complex with (Rp)-SPMPApp | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4CP5 | Ndpk in complex with (rp)-spmpapp | x-ray diffraction | A, B, C, D, E, F | — | — |
| P22887 | AlphaFold monomer V2.0 prediction for nucleoside diphosphate kinase, cytosolic (P22887) | predicted | A | — | 1 (best 0.53) |
Experiment against prediction
- 3FKB chain A against the predicted model P22887: TM-score 0.99, RMSD 0.36 Å
- 3FKB chain A against the predicted model P22887: TM-score 0.99, RMSD 0.36 Å
- 4C6A chain A against the predicted model P22887: TM-score 0.99, RMSD 0.35 Å
- 4C6A chain A against the predicted model P22887: TM-score 0.99, RMSD 0.35 Å
- 1NPK chain A against the predicted model P22887: TM-score 0.99, RMSD 0.37 Å
- 1NPK chain A against the predicted model P22887: TM-score 0.99, RMSD 0.37 Å
- 1NDK chain A against the predicted model P22887: TM-score 0.99, RMSD 0.37 Å
- 1NDK chain A against the predicted model P22887: TM-score 0.99, RMSD 0.37 Å
- 1NCL chain A against the predicted model P22887: TM-score 0.99, RMSD 0.38 Å
- 1NCL chain A against the predicted model P22887: TM-score 0.99, RMSD 0.38 Å
Elsewhere
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