UniProt P18670
Agglutinin alpha chain (P18670)
Agglutinin alpha chain (UniProt P18670): 48 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P18670
- Protein
- Agglutinin alpha chain
- Experimental structures
- 48
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 13 · 2 records with a druggable one
Structures
49 records of P18670 in the MolNFT archive: 48 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JAC | A novel mode of carbohydrate recognition in jacalin, a moraceae plant lectin with a beta-prism | x-ray diffraction | A, C, E, G | — | — |
| 1JAC | A novel mode of carbohydrate recognition in jacalin, a moraceae plant lectin with a beta-prism | x-ray diffraction | A, C, E, G | — | — |
| 1KU8 | Crystal structure of Jacalin | x-ray diffraction | A, C, E, G | — | — |
| 1KU8 | Crystal structure of jacalin | x-ray diffraction | A, C, E, G | — | — |
| 1KUJ | Crystal structure of Jacalin complexed with 1-O-methyl-alpha-D-mannose | x-ray diffraction | A, C, E, G | — | — |
| 1KUJ | Crystal structure of jacalin complexed with 1-O-methyl-alpha-D-mannose | x-ray diffraction | A, C, E, G | — | — |
| 1PXD | Crystal structure of the complex of jacalin with meso-tetrasulphonatophenylporphyrin. | x-ray diffraction | A | — | — |
| 1PXD | Crystal structure of the complex of jacalin with meso- tetrasulphonatophenylporphyrin. | x-ray diffraction | A | — | — |
| 1UGW | Crystal structure of jacalin- Gal complex | x-ray diffraction | A, C, E, G | — | — |
| 1UGW | Crystal structure of jacalin- gal complex | x-ray diffraction | A, C, E, G | — | — |
| 1UGX | Crystal structure of jacalin- Me-alpha-T-antigen (Gal-beta(1-3)-GalNAc-alpha-o-Me) complex | x-ray diffraction | A | — | — |
| 1UGX | Crystal structure of jacalin- me-alpha-T-antigen (gal-BETA(1-3)- galnac-alpha-O-me) complex | x-ray diffraction | A | — | — |
| 1UGY | Crystal structure of jacalin- mellibiose (Gal-alpha(1-6)-Glc) complex | x-ray diffraction | A, C, E, G | — | — |
| 1UGY | Crystal structure of jacalin- mellibiose (gal-ALPHA(1-6)-glc) complex | x-ray diffraction | A, C, E, G | — | — |
| 1UH0 | Crystal structure of jacalin- Me-alpha-GalNAc complex | x-ray diffraction | A, C, E, G | — | — |
| 1UH0 | Crystal structure of jacalin- me-alpha-galnac complex | x-ray diffraction | A, C, E, G | — | — |
| 1UH1 | Crystal structure of jacalin- GalNAc-beta(1-3)-Gal-alpha-O-Me complex | x-ray diffraction | A, C, E, G | — | — |
| 1UH1 | Crystal structure of jacalin- galnac-BETA(1-3)-gal-alpha-O-me complex | x-ray diffraction | A, C, E, G | — | — |
| 1WS4 | Crystal structure of Jacalin- Me-alpha-Mannose complex: Promiscuity vs Specificity | x-ray diffraction | A, C, E, G | — | — |
| 1WS4 | Crystal structure of jacalin- me-alpha-mannose complex: promiscuity vs specificity | x-ray diffraction | A, C, E, G | — | — |
| 1WS5 | Crystal structure of Jacalin-Me-alpha-Mannose complex: Promiscuity vs Specificity | x-ray diffraction | A, C, E, G | — | — |
| 1WS5 | Crystal structure of jacalin-me-alpha-mannose complex: promiscuity vs specificity | x-ray diffraction | A, C, E, G | — | — |
| 4AK4 | High resolution structure of Galactose Binding lectin from Champedak (CGB) | x-ray diffraction | A, C, E, G, I, K, M, O | — | — |
| 4AK4 | High resolution structure of galactose binding lectin from champedak (cgb) | x-ray diffraction | A, C, E, G, I, K, M, O | — | — |
| 4AKB | Structure of Galactose Binding lectin from Champedak (CGB) with Galactose | x-ray diffraction | A, C, E, G | — | — |
| 4AKB | Structure of galactose binding lectin from champedak (cgb) with galactose | x-ray diffraction | A, C, E, G | — | — |
| 4AKC | Structure of Galactose Binding lectin from Champedak (CGB) with Gal(beta)1,3-GalNac | x-ray diffraction | A, C, E, G | — | — |
| 4AKC | Structure of galactose binding lectin from champedak (cgb) with GAL(BETA)1,3-galnac | x-ray diffraction | A, C, E, G | — | — |
| 4R6N | Jacalin-carbohydrate interactions. Distortion of the ligand as a determinant of affinity | x-ray diffraction | A, C, E, G | — | — |
| 4R6N | Jacalin-carbohydrate interactions. distortion of the ligand as a determinant of affinity | x-ray diffraction | A, C, E, G | — | — |
| 4R6O | Jacalin-carbohydrate interactions. Distortion of the ligand as a determinant of affinity. | x-ray diffraction | A, C, E, G | — | — |
| 4R6O | Jacalin-carbohydrate interactions. distortion of the ligand as a determinant of affinity. | x-ray diffraction | A, C, E, G | — | — |
| 4R6P | Jacalin-carbohydrate interactions. Distortion of the ligand as a determinant of affinity. | x-ray diffraction | A, C, E, G | — | — |
| 4R6P | Jacalin-carbohydrate interactions. distortion of the ligand as a determinant of affinity. | x-ray diffraction | A, C, E, G | — | — |
| 4R6Q | Jacalin-carbohydrate interactions. Distortion of the ligand as a determinant of affinity. | x-ray diffraction | A, C, E, G | — | — |
| 4R6Q | Jacalin-carbohydrate interactions. distortion of the ligand as a determinant of affinity. | x-ray diffraction | A, C, E, G | — | — |
| 4R6R | Jacalin-carbohydrate interactions. Distortion of the ligand as a determinant of affinity. | x-ray diffraction | A, C, E, G | — | — |
| 4R6R | Jacalin-carbohydrate interactions. distortion of the ligand as a determinant of affinity. | x-ray diffraction | A, C, E, G | — | — |
| 5J4T | Structure of tetrameric jacalin complexed with GlcNAc beta-(1,3) Gal-beta-OMe | x-ray diffraction | A, C, E, G | MBG, NAG | 6 (best 0.82) |
| 5J4T | Structure of tetrameric jacalin complexed with glcnac beta-(1,3) gal- beta-ome | x-ray diffraction | A, C, E, G | — | — |
| 5J4X | Structure of tetrameric jacalin complexed with Gal beta-(1,3) Gal-beta-OMe | x-ray diffraction | A, C, E, G | MBG, GAL | — |
| 5J4X | Structure of tetrameric jacalin complexed with gal beta-(1,3) gal- beta-ome | x-ray diffraction | A, C, E, G | — | — |
| 5J50 | Structure of tetrameric jacalin complexed with Gal beta-(1,3) GalNAc-alpha-OPNP | x-ray diffraction | A, C, E, G | A2G, GAL, NPO | 7 (best 0.83) |
| 5J50 | Structure of tetrameric jacalin complexed with gal beta-(1,3) galnac- alpha-opnp | x-ray diffraction | A, C, E, G | — | — |
| 5J51 | Structure of tetrameric jacalin complexed with Gal alpha-(1,4) Gal | x-ray diffraction | A, C, E, G | GLA | — |
| 5J51 | Structure of tetrameric jacalin complexed with gal alpha-(1,4) gal | x-ray diffraction | A, C, E, G | — | — |
| 5JM1 | Structure of tetrameric jacalin complexed with a trisaccharide, Gal alpha-(1,3) Gal beta-(1,4) Gal | x-ray diffraction | A, C, E, G | GAL, GLA, AMG | — |
| 5JM1 | Structure of tetrameric jacalin complexed with a trisaccharide, gal alpha-(1,3) gal beta-(1,4) gal | x-ray diffraction | A, C, E, G | — | — |
| P18670 | AlphaFold monomer V2.0 prediction for agglutinin alpha chain (P18670) | predicted | A | — | — |
Ligands
- GAL · beta-D-galactopyranose · in 3 records
- GLA · alpha-D-galactopyranose · in 2 records
- MBG · methyl beta-D-galactopyranoside · in 2 records
- A2G · 2-acetamido-2-deoxy-alpha-D-galactopyranose · in 1 record
- AMG · methyl alpha-D-galactopyranoside · in 1 record
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
- NPO · P-nitrophenol · in 1 record
Experiment against prediction
- 1UGX chain A against the predicted model P18670: TM-score 1.00, RMSD 0.18 Å
- 1UGX chain A against the predicted model P18670: TM-score 1.00, RMSD 0.18 Å
- 1WS4 chain C against the predicted model P18670: TM-score 1.00, RMSD 0.19 Å
- 1WS4 chain C against the predicted model P18670: TM-score 1.00, RMSD 0.19 Å
- 1UGW chain C against the predicted model P18670: TM-score 1.00, RMSD 0.19 Å
- 1UGW chain C against the predicted model P18670: TM-score 1.00, RMSD 0.19 Å
- 1WS5 chain C against the predicted model P18670: TM-score 1.00, RMSD 0.20 Å
- 1WS5 chain C against the predicted model P18670: TM-score 1.00, RMSD 0.20 Å
- 1UH0 chain A against the predicted model P18670: TM-score 1.00, RMSD 0.20 Å
- 1UH0 chain A against the predicted model P18670: TM-score 1.00, RMSD 0.20 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.