Crystal structure of jacalin- me-alpha-T-antigen (gal-BETA(1-3)- galnac-alpha-O-me) complex

Structure

x-ray diffraction · 2 distinct chains · 0% helix, 63% strand (DSSP).

Ligands and binding sites

• MGC · methyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside · ligand · chains A
• GAL · beta-D-galactopyranose · sugar · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 541 Ų buried · 7 hydrogen bonds · protein-protein

Compared structures

• 1UGX · Crystal structure of jacalin- Me-alpha-T-antigen (Gal-beta(1-3)-GalNAc-alpha-o-Me) complex · the same entry in another collection · chain A against A, TM-score 1.00
• P18670 · AlphaFold monomer V2.0 prediction for agglutinin alpha chain (P18670) · a predicted model of the same protein · chain A against A, TM-score 1.00
• P18673 · AlphaFold monomer V2.0 prediction for agglutinin beta-3 chain (P18673) · a predicted model of the same protein · chain B against A, TM-score 0.34

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P18670
• Every structure of UniProt P18673
• Elsewhere: RCSB PDB 1UGX · PDBe 1UGX · UniProt P18670 · UniProt P18673