UniProt P14350
Integrase (P14350)
Integrase (UniProt P14350), EC 2.7.7.-, 2.7.7.49: 109 experimental structures on GenesisL1, 9 ligands bound, 7 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P14350
- Protein
- Integrase
- EC
- 2.7.7.-, 2.7.7.49, 2.7.7.7, 3.1.-.-, 3.1.26.4, 3.4.23.-
- Experimental structures
- 109
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 7 · 1 record with a druggable one
Structures
109 records of P14350 in the MolNFT archive: 109 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LSN | Solution structure of PFV RNase H domain | solution nmr | A | — | — |
| 2LSN | Solution structure of pfv RNase H domain | solution nmr | A | — | — |
| 2X6N | Human foamy virus integrase - catalytic core. Manganese-bound structure. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2X6N | Human foamy virus integrase - catalytic core. manganese- bound structure. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2X6S | Human foamy virus integrase - catalytic core. Magnesium-bound structure. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2X6S | Human foamy virus integrase - catalytic core. magnesium- bound structure. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2X74 | Human foamy virus integrase - catalytic core. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2X74 | Human foamy virus integrase - catalytic core. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2X78 | Human foamy virus integrase - catalytic core. | x-ray diffraction | A, B, C | — | — |
| 2X78 | Human foamy virus integrase - catalytic core. | x-ray diffraction | A, B, C | — | — |
| 3DLR | Crystal structure of the catalytic core domain from PFV integrase | x-ray diffraction | A | — | — |
| 3DLR | Crystal structure of the catalytic core domain from pfv integrase | x-ray diffraction | A | — | — |
| 3L2Q | Crystal structure of the Prototype Foamy Virus (PFV) intasome in apo form | x-ray diffraction | A, B | — | — |
| 3L2Q | Crystal structure of the prototype foamy virus (pfv) intasome in apo form | x-ray diffraction | A, B | — | — |
| 3L2R | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium | x-ray diffraction | A, B | — | — |
| 3L2R | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium | x-ray diffraction | A, B | — | — |
| 3L2U | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and GS9137… | x-ray diffraction | A, B | — | — |
| 3L2U | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and GS9137… | x-ray diffraction | A, B | — | — |
| 3L2V | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and MK0518… | x-ray diffraction | A, B | — | — |
| 3L2V | Crystal structure of the prototype foamy virus (pfv) intasome in complex with manganese and MK0518… | x-ray diffraction | A, B | — | — |
| 3L2W | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and GS9137… | x-ray diffraction | A, B | — | — |
| 3L2W | Crystal structure of the prototype foamy virus (pfv) intasome in complex with manganese and GS9137… | x-ray diffraction | A, B | — | — |
| 3OS0 | PFV strand transfer complex (STC) at 2.81 A resolution | x-ray diffraction | A, B | — | — |
| 3OS0 | Pfv strand transfer complex (stc) at 2.81 a resolution | x-ray diffraction | A, B | — | — |
| 3OS1 | PFV target capture complex (TCC) at 2.97 A resolution | x-ray diffraction | A, B | — | — |
| 3OS1 | Pfv target capture complex (tcc) at 2.97 a resolution | x-ray diffraction | A, B | — | — |
| 3OS2 | PFV target capture complex (TCC) at 3.32 A resolution | x-ray diffraction | A, B | — | — |
| 3OS2 | Pfv target capture complex (tcc) at 3.32 a resolution | x-ray diffraction | A, B | — | — |
| 3OY9 | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese at 2.55… | x-ray diffraction | A, B | — | — |
| 3OY9 | Crystal structure of the prototype foamy virus (pfv) intasome in complex with manganese at 2.55… | x-ray diffraction | A, B | — | — |
| 3OYA | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and… | x-ray diffraction | A, B | — | — |
| 3OYA | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and… | x-ray diffraction | A, B | — | — |
| 3OYB | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYB | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYC | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYC | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYD | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYD | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYE | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYE | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYF | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYF | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYG | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYG | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYH | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYH | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the… | x-ray diffraction | A, B | — | — |
| 3OYI | Crystal structure of the PFV S217Q mutant intasome in complex with manganese | x-ray diffraction | A, B | — | — |
| 3OYI | Crystal structure of the pfv S217Q mutant intasome in complex with manganese | x-ray diffraction | A, B | — | — |
| 3OYJ | Crystal structure of the PFV S217Q mutant intasome in complex with magnesium and the INSTI MK2048 | x-ray diffraction | A, B | — | — |
| 3OYJ | Crystal structure of the pfv S217Q mutant intasome in complex with magnesium and the insti MK2048 | x-ray diffraction | A, B | — | — |
| 3OYK | Crystal structure of the PFV S217H mutant intasome bound to manganese | x-ray diffraction | A, B | — | — |
| 3OYK | Crystal structure of the pfv S217H mutant intasome bound to manganese | x-ray diffraction | A, B | — | — |
| 3OYL | Crystal structure of the PFV S217H mutant intasome bound to magnesium and the INSTI MK2048 | x-ray diffraction | A, B | — | — |
| 3OYL | Crystal structure of the pfv S217H mutant intasome bound to magnesium and the insti MK2048 | x-ray diffraction | A, B | — | — |
| 3OYM | Crystal structure of the PFV N224H mutant intasome bound to manganese | x-ray diffraction | A, B | — | — |
| 3OYM | Crystal structure of the pfv N224H mutant intasome bound to manganese | x-ray diffraction | A, B | — | — |
| 3OYN | Crystal structure of the PFV N224H mutant intasome bound to magnesium and the INSTI MK2048 | x-ray diffraction | A, B | — | — |
| 3OYN | Crystal structure of the pfv N224H mutant intasome bound to magnesium and the insti MK2048 | x-ray diffraction | A, B | — | — |
| 3S3M | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and… | x-ray diffraction | A, B | — | — |
| 3S3M | Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and… | x-ray diffraction | A, B | — | — |
49 records more on the page itself.
Ligands
- MG · Magnesium ion · in 11 records
- SO4 · Sulfate ion · in 10 records
- ZN · Zinc ion · in 10 records
- OUY · Methyl 3-[5-azanyl-6-[[2,4-bis(fluoranyl) phenyl]methylcarbamoyl]-8-oxidanyl-7-oxidanylidene-1, 8-naphthyridin-3-yl]propanoate · in 2 records
- R7K · ~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-5-(hydroxymethyl)-1,4-bis(oxidanyl)-2-oxidanylidene-1,8-naphthyridine-3-carboxamide · in 2 records
- 8G1 · (3R)-8-[(3-chloro-4-fluorophenyl)methyl]-6-hydroxy-1,5, 7-trioxo-1,2',3',5,7,8,9,10-octahydro-2H-spiro[imidazo[5,1-a][2,6]naphthyridine-3,1'-indene]-7'-carbonitrile · in 1 record
- 8G4 · (1S,2S,5R)-8'-[(3-chloro-4-fluorophenyl)methyl]-2'-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]-6'-hydroxy-9',10'-dihydro-2'H-spiro[bicyclo[3.1.0]hexane-2,3'-imidazo[5,1-a][2,6]naphthyridine]-1',5',7'(8'H)-trione · in 1 record
- R7N · 4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[2-(2-morpholin-4-ylethylsulfonyl)ethyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide · in 1 record
- XZ4 · Methyl 2-[[3-[[2,4-bis(fluoranyl) phenyl]methylcarbamoyl]-7-methoxy-1-oxidanyl-2-oxidanylidene-1,8-naphthyridin-4-yl]amino]ethanoate · in 1 record
Elsewhere
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