GL1X · GenesisL1 explorer

Ligand · ZYO

ZYO · (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-6-methyl-4-(5-methyl-1,1-dioxido-1,2,5-thiadiazolidin-2-yl)-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-dione

ZYO, (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-6-methyl-4-(5-methyl-1,1-dioxido-1,2,5-thiadiazolidin-2-yl)-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-dione (C22 H24 Cl F N6 O5 S, 539.0 g/mol), in the MolNFT…

Component
ZYO
Formula
C22 H24 Cl F N6 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

ZYO in 2 structures; the first of them:

  • 3OYG · Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium… · ZYO A398 · binds ASP128, TYR129, ASP185, GLN186, GLY187, TYR212, HIS213, PRO214 and 5 more
  • 3OYG · Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium… · ZYO A398 · binds ASP128, TYR129, ASP185, GLN186, GLY187, TYR212, HIS213, PRO214 and 5 more

Residues it binds most

ASP 2, GLN 2, TYR 2, DA 2, DC 2, DG 2, GLU 2, GLY 2, HIS 2, PRO 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • NH4 · Ammonium ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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