RLT · N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl) carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide

Binding sites

RLT in 6 structures; the first of them:

• 7LW6 · The crystal structure of the 2009/H1N1/California PA endonuclease I38T mutant in complex… · RLT A201 · binds TYR24, HIS41, GLU80, TRP88, LYS104, PHE105, LEU106, PRO107 and 4 more
• 7M0N · The crystal structure of wild type PA endonuclease (A/Vietnam/1203/2004) in complex with… · RLT A301 · binds TYR24, HIS41, GLU80, TRP88, LYS104, PHE105, LEU106, ASP108 and 6 more
• 7OUG · STLV-1 intasome:B56 in complex with the strand-transfer inhibitor raltegravir · RLT E304 · binds ASP65, ASP122, ASN123, PRO148, TYR149, PRO151, THR152, GLU158 and 3 more
• 7LW6 · The crystal structure of the 2009/H1N1/CALIFORNIA pa endonuclease I38T mutant in complex… · RLT A201 · binds HIS41, GLU80, PHE105, LEU106, PRO107, ASP108, GLU119, ILE120 and 1 more
• 7M0N · The crystal structure of wild type pa endonuclease (2009/H1N1/CALIFORNIA) in complex with… · RLT A301 · binds TYR24, HIS41, GLU80, LYS104, PHE105, LEU106, ASP108, GLU119 and 5 more
• 7OUG · Stlv-1 INTASOME:B56 in complex with the strand-transfer inhibitor raltegravir · RLT E304 · binds ASP65, ASP122, ASN123, PRO148, TYR149, PRO151, THR152, GLU158 and 3 more

Residues it binds most

GLU 14, TYR 14, LYS 9, ASP 14, HIS 10, ILE 10, LEU 10, PHE 10, PRO 6, ARG 6 (residue and the binding sites it lines).

Found with

• MN · Manganese (II) ion
• SO4 · Sulfate ion
• QQ4 · Hexa Vinylpyrrolidone K15
• MG · Magnesium ion
• ZN · Zinc ion
• GOL · Glycerol