UniProt P10275
Androgen receptor (P10275)
Androgen receptor (UniProt P10275): 164 experimental structures and 1 predicted model on GenesisL1, 9 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P10275
- Protein
- Androgen receptor
- Experimental structures
- 164
- Predicted models
- 1
- Ligands
- 9
- Pockets
- 23 · 5 records with a druggable one
Structures
165 records of P10275 in the MolNFT archive: 164 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1E3G | Human Androgen Receptor Ligand Binding in complex with the ligand metribolone (R1881) | x-ray diffraction | A | — | — |
| 1E3G | Human androgen receptor ligand binding in complex with the ligand metribolone (R1881) | x-ray diffraction | A | — | — |
| 1GS4 | Structural basis for the glucocorticoid response in a mutant human androgen receptor (ARccr)… | x-ray diffraction | A | — | — |
| 1GS4 | Structural basis for the glucocorticoid response in a mutant human androgen receptor (arccr)… | x-ray diffraction | A | — | — |
| 1T5Z | Crystal Structure of the Androgen Receptor Ligand Binding Domain (LBD) with DHT and a peptide… | x-ray diffraction | A | — | — |
| 1T5Z | Crystal structure of the androgen receptor ligand binding domain (lbd) with dht and a peptide… | x-ray diffraction | A | — | — |
| 1T63 | Crystal Structure of the Androgen Receptor Ligand Binding Domain with DHT and a peptide derived… | x-ray diffraction | A | — | — |
| 1T63 | Crystal structure of the androgen receptor ligand binding domain with dht and a peptide derived… | x-ray diffraction | A | — | — |
| 1T65 | Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived… | x-ray diffraction | A | — | — |
| 1T65 | Crystal structure of the androgen receptor ligand binding domain with dht and a peptide derived… | x-ray diffraction | A | — | — |
| 1XJ7 | Complex Androgen Receptor LBD and RAC3 peptide | x-ray diffraction | A | — | — |
| 1XJ7 | Complex androgen receptor lbd and RAC3 peptide | x-ray diffraction | A | — | — |
| 1XOW | Crystal structure of the human androgen receptor ligand binding domain bound with an androgen… | x-ray diffraction | A, B | — | — |
| 1XOW | Crystal structure of the human androgen receptor ligand binding domain bound with an androgen… | x-ray diffraction | A, B | — | — |
| 1XQ3 | Crystal structure of the human androgen receptor ligand binding domain bound with R1881 | x-ray diffraction | A | — | — |
| 1XQ3 | Crystal structure of the human androgen receptor ligand binding domain bound with R1881 | x-ray diffraction | A | — | — |
| 1Z95 | Crystal Structure of the Androgen Receptor Ligand-binding Domain W741L Mutant Complex with… | x-ray diffraction | A | — | — |
| 1Z95 | Crystal structure of the androgen receptor ligand-binding domain W741L mutant complex with… | x-ray diffraction | A | — | — |
| 2AM9 | Crystal structure of human androgen receptor ligand binding domain in complex with testosterone | x-ray diffraction | A | — | — |
| 2AM9 | Crystal structure of human androgen receptor ligand binding domain in complex with testosterone | x-ray diffraction | A | — | — |
| 2AMA | Crystal structure of human androgen receptor ligand binding domain in complex with… | x-ray diffraction | A | — | — |
| 2AMA | Crystal structure of human androgen receptor ligand binding domain in complex with… | x-ray diffraction | A | — | — |
| 2AMB | Crystal structure of human androgen receptor ligand binding domain in complex with tetrahydrogestri | x-ray diffraction | A | — | — |
| 2AMB | Crystal structure of human androgen receptor ligand binding domain in complex with… | x-ray diffraction | A | — | — |
| 2AO6 | Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(iii) 740-753… | x-ray diffraction | A | — | — |
| 2AO6 | Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(III) 740-753… | x-ray diffraction | A | — | — |
| 2AX6 | Crystal Structure Of The Androgen Receptor Ligand Binding Domain T877A Mutant In Complex With… | x-ray diffraction | A | — | — |
| 2AX6 | Crystal structure of the androgen receptor ligand binding domain T877A mutant in complex with… | x-ray diffraction | A | — | — |
| 2AX7 | Crystal Structure Of The Androgen Receptor Ligand Binding Domain T877A Mutant In Complex With S-1 | x-ray diffraction | A | — | — |
| 2AX7 | Crystal structure of the androgen receptor ligand binding domain T877A mutant in complex with S-1 | x-ray diffraction | A | — | — |
| 2AX8 | Crystal Structure Of The Androgen Receptor Ligand Binding Domain W741L Mutant In Complex With S-1 | x-ray diffraction | A | — | — |
| 2AX8 | Crystal structure of the androgen receptor ligand binding domain W741L mutant in complex with S-1 | x-ray diffraction | A | — | — |
| 2AX9 | Crystal Structure Of The Androgen Receptor Ligand Binding Domain In Complex With R-3 | x-ray diffraction | A | — | — |
| 2AX9 | Crystal structure of the androgen receptor ligand binding domain in complex with R-3 | x-ray diffraction | A | — | — |
| 2AXA | Crystal Structure Of The Androgen Receptor Ligand Binding Domain In Complex With S-1 | x-ray diffraction | A | — | — |
| 2AXA | Crystal structure of the androgen receptor ligand binding domain in complex with S-1 | x-ray diffraction | A | — | — |
| 2HVC | The Crystal Structure of Ligand-binding Domain (LBD) of human Androgen Receptor in Complex with a… | x-ray diffraction | A | — | — |
| 2HVC | The crystal structure of ligand-binding domain (lbd) of human androgen receptor in complex with a… | x-ray diffraction | A | — | — |
| 2OZ7 | Crystal structure of the human androgen receptor T877A mutant ligand-binding domain with… | x-ray diffraction | A | — | — |
| 2OZ7 | Crystal structure of the human androgen receptor T877A mutant ligand- binding domain with… | x-ray diffraction | A | — | — |
| 2PIO | Androgen receptor LBD with small molecule | x-ray diffraction | A | — | — |
| 2PIO | Androgen receptor lbd with small molecule | x-ray diffraction | A | — | — |
| 2PIP | Androgen receptor LBD with small molecule | x-ray diffraction | L | — | — |
| 2PIP | Androgen receptor lbd with small molecule | x-ray diffraction | L | — | — |
| 2PIQ | androgen receptor LBD with small molecule | x-ray diffraction | A | — | — |
| 2PIQ | Androgen receptor lbd with small molecule | x-ray diffraction | A | — | — |
| 2PIR | Androgen receptor LBD with small molecule | x-ray diffraction | A | — | — |
| 2PIR | Androgen receptor lbd with small molecule | x-ray diffraction | A | — | — |
| 2PIT | Androgen receptor LBD with small molecule | x-ray diffraction | A | — | — |
| 2PIT | Androgen receptor lbd with small molecule | x-ray diffraction | A | — | — |
| 2PIU | Androgen receptor LBD with small molecule | x-ray diffraction | A | — | — |
| 2PIU | Androgen receptor lbd with small molecule | x-ray diffraction | A | — | — |
| 2PIV | Androgen receptor with small molecule | x-ray diffraction | A | — | — |
| 2PIV | Androgen receptor with small molecule | x-ray diffraction | A | — | — |
| 2PIW | Androgen receptor with small molecule | x-ray diffraction | A | — | — |
| 2PIW | Androgen receptor with small molecule | x-ray diffraction | A | — | — |
| 2PIX | AR LBD with small molecule | x-ray diffraction | A | — | — |
| 2PIX | Ar lbd with small molecule | x-ray diffraction | A | — | — |
| 2PKL | Androgen receptor LBD with small molecule | x-ray diffraction | A | — | — |
| 2PKL | Androgen receptor lbd with small molecule | x-ray diffraction | A | — | — |
105 records more on the page itself.
Ligands
- DHT · 5-alpha-dihydrotestosterone · in 5 records
- SO4 · Sulfate ion · in 4 records
- 51Y · 2-chloro-4-{[(1R,2R)-2-hydroxy-2-methylcyclopentyl]amino}-3-methylbenzonitrile · in 1 record
- 77T · 2-fluoro-4-[(2S,3S)-3-hydroxy-2,3-dimethylpyrrolidin-1-yl]-3-methylbenzonitrile · in 1 record
- 77U · 2-chloro-4-[(2S,3S)-3-hydroxy-2-methylpyrrolidin-1-yl]-3-methylbenzonitrile · in 1 record
- 97A · 4-[(2S,3S)-2-ethyl-3-hydroxy-5-oxopyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile · in 1 record
- 9FG · 5-(2-fluoro-4-hydroxyphenyl)-1-methyl-1H-pyrrole-2-carbonitrile · in 1 record
- CL · Chloride ion · in 1 record
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 5CJ6 chain A against the predicted model P10275: TM-score 0.99, RMSD 0.51 Å
- 5CJ6 chain A against the predicted model P10275: TM-score 0.99, RMSD 0.51 Å
- 2AO6 chain A against the predicted model P10275: TM-score 0.99, RMSD 0.51 Å
- 2AO6 chain A against the predicted model P10275: TM-score 0.99, RMSD 0.51 Å
- 2PIO chain A against the predicted model P10275: TM-score 0.99, RMSD 0.53 Å
- 2PIO chain A against the predicted model P10275: TM-score 0.99, RMSD 0.53 Å
- 4OGH chain A against the predicted model P10275: TM-score 0.99, RMSD 0.52 Å
- 4OGH chain A against the predicted model P10275: TM-score 0.99, RMSD 0.52 Å
- 1XOW chain A against the predicted model P10275: TM-score 0.99, RMSD 0.53 Å
- 1XOW chain A against the predicted model P10275: TM-score 0.99, RMSD 0.53 Å
Elsewhere
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