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Ligand · FHM

FHM · S-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

FHM, S-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (C17 H14 F4 N2 O5, 402.3 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues…

Component
FHM
Formula
C17 H14 F4 N2 O5
Class
ligand
Structures
6
PDB entries
3

Binding sites

FHM in 6 structures; the first of them:

  • 2AX7 · Crystal Structure Of The Androgen Receptor Ligand Binding Domain T877A Mutant In Complex… · FHM A1 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, GLN738, TRP741 and 16 more
  • 2AX8 · Crystal Structure Of The Androgen Receptor Ligand Binding Domain W741L Mutant In Complex… · FHM A1 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, GLN738, LEU741 and 15 more
  • 2AXA · Crystal Structure Of The Androgen Receptor Ligand Binding Domain In Complex With S-1 · FHM A1 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, GLN738, TRP741 and 15 more
  • 2AX7 · Crystal structure of the androgen receptor ligand binding domain T877A mutant in complex… · FHM A1 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, GLN738, TRP741 and 16 more
  • 2AX8 · Crystal structure of the androgen receptor ligand binding domain W741L mutant in complex… · FHM A1 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, GLN738, LEU741 and 15 more
  • 2AXA · Crystal structure of the androgen receptor ligand binding domain in complex with S-1 · FHM A1 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, GLN738, TRP741 and 15 more

Residues it binds most

MET 6, LEU 6, GLN 6, ILE 6, VAL 6, PHE 6, ARG 6, ASN 6, GLY 6, HIS 6 (residue and the binding sites it lines).

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