GL1X · GenesisL1 explorer

Ligand · R18

R18 · (17beta)-17-hydroxy-17-methylestra-4,9,11-trien-3-one

R18, (17beta)-17-hydroxy-17-methylestra-4,9,11-trien-3-one (C19 H24 O2, 284.4 g/mol), in the MolNFT structures on GenesisL1: bound in 10 records (5 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
R18
Formula
C19 H24 O2
Class
ligand
Structures
10
PDB entries
5

Binding sites

R18 in 10 structures; the first of them:

  • 1E3G · Human Androgen Receptor Ligand Binding in complex with the ligand metribolone (R1881) · R18 A1000 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, MET742, MET745 and 12 more
  • 1E3K · Human Progesteron Receptor Ligand Binding Domain in complex with the ligand metribolone… · R18 A1000 · binds LEU715, LEU718, ASN719, LEU721, GLY722, GLN725, TRP755, MET756 and 11 more
  • 1XOW · Crystal structure of the human androgen receptor ligand binding domain bound with an… · R18 A1001 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, TRP741, MET742 and 13 more
  • 1XQ3 · Crystal structure of the human androgen receptor ligand binding domain bound with R1881 · R18 A1001 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, TRP741, MET742 and 11 more
  • 2AO6 · Crystal structure of the human androgen receptor ligand binding domain bound with… · R18 A1001 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, MET742, MET745 and 12 more
  • 1E3G · Human androgen receptor ligand binding in complex with the ligand metribolone (R1881) · R18 A1000 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, MET742, MET745 and 12 more
  • 1E3K · Human progesteron receptor ligand binding domain in complex with the ligand metribolone… · R18 A1000 · binds LEU715, LEU718, ASN719, LEU721, GLY722, GLN725, TRP755, MET756 and 11 more
  • 1XOW · Crystal structure of the human androgen receptor ligand binding domain bound with an… · R18 A1001 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, TRP741, MET742 and 13 more
  • 1XQ3 · Crystal structure of the human androgen receptor ligand binding domain bound with R1881 · R18 A1001 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, TRP741, MET742 and 11 more
  • 2AO6 · Crystal structure of the human androgen receptor ligand binding domain bound with… · R18 A1001 · binds LEU701, LEU704, ASN705, LEU707, GLY708, GLN711, MET742, MET745 and 12 more

Residues it binds most

LEU 12, MET 12, PHE 12, ARG 12, ASN 12, GLN 12, VAL 12, GLY 10, THR 8, TRP 8 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.