UniProt P08170
Seed linoleate 13S-lipoxygenase-1 (P08170)
Seed linoleate 13S-lipoxygenase-1 (UniProt P08170), EC 1.13.11.12: 42 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P08170
- Protein
- Seed linoleate 13S-lipoxygenase-1
- EC
- 1.13.11.12
- Experimental structures
- 42
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
43 records of P08170 in the MolNFT archive: 42 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1F8N | Lipoxygenase-1 (soybean) at 100K, new refinement | x-ray diffraction | A | — | — |
| 1F8N | Lipoxygenase-1 (soybean) at 100K, new refinement | x-ray diffraction | A | — | — |
| 1FGM | Lipoxygenase-1 (soybean) at 100K, N694H mutant | x-ray diffraction | A | — | — |
| 1FGM | Lipoxygenase-1 (soybean) at 100K, N694H mutant | x-ray diffraction | A | — | — |
| 1FGO | Lipoxygenase-1 (soybean) at 100K, Q495A mutant | x-ray diffraction | A | — | — |
| 1FGO | Lipoxygenase-1 (soybean) at 100K, Q495A mutant | x-ray diffraction | A | — | — |
| 1FGQ | Lipoxygenase-1 (soybean) at 100K, Q495E mutant | x-ray diffraction | A | — | — |
| 1FGQ | Lipoxygenase-1 (soybean) at 100K, Q495E mutant | x-ray diffraction | A | — | — |
| 1FGR | Lipoxygenase-1 (soybean) at 100K, Q697E mutant | x-ray diffraction | A | — | — |
| 1FGR | Lipoxygenase-1 (soybean) at 100K, Q697E mutant | x-ray diffraction | A | — | — |
| 1FGT | Lipoxygenase-1 (soybean) at 100K, Q697N mutant | x-ray diffraction | A | — | — |
| 1FGT | Lipoxygenase-1 (soybean) at 100K, Q697N mutant | x-ray diffraction | A | — | — |
| 1Y4K | Lipoxygenase-1 (Soybean) at 100K, N694G Mutant | x-ray diffraction | A | — | — |
| 1Y4K | Lipoxygenase-1 (soybean) at 100K, N694G mutant | x-ray diffraction | A | — | — |
| 1YGE | Lipoxygenase-1 (soybean) at 100K | x-ray diffraction | A | — | — |
| 1YGE | Lipoxygenase-1 (soybean) at 100K | x-ray diffraction | A | — | — |
| 2SBL | The three-dimensional structure of an arachidonic acid 15-lipoxygenase | x-ray diffraction | B, A | — | — |
| 2SBL | The three-dimensional structure of an arachidonic acid 15- lipoxygenase | x-ray diffraction | B, A | — | — |
| 3BNB | Lipoxygenase-1 (Soybean) I553L Mutant | x-ray diffraction | A | — | — |
| 3BNB | Lipoxygenase-1 (soybean) I553L mutant | x-ray diffraction | A | — | — |
| 3BNC | Lipoxygenase-1 (Soybean) I553G Mutant | x-ray diffraction | A | — | — |
| 3BNC | Lipoxygenase-1 (soybean) I553G mutant | x-ray diffraction | A | — | — |
| 3BND | Lipoxygenase-1 (Soybean), I553V Mutant | x-ray diffraction | A | — | — |
| 3BND | Lipoxygenase-1 (soybean), I553V mutant | x-ray diffraction | A | — | — |
| 3BNE | Lipoxygenase-1 (Soybean) I553A Mutant | x-ray diffraction | A | — | — |
| 3BNE | Lipoxygenase-1 (soybean) I553A mutant | x-ray diffraction | A | — | — |
| 3PZW | Soybean lipoxygenase-1 - re-refinement | x-ray diffraction | A | — | — |
| 3PZW | Soybean lipoxygenase-1 - re-refinement | x-ray diffraction | A | — | — |
| 4WFO | manganese-substituted soybean lipoxygenase-1 | x-ray diffraction | A | — | — |
| 4WFO | Manganese-substituted soybean lipoxygenase-1 | x-ray diffraction | A | — | — |
| 4WHA | Lipoxygenase-1 (soybean) L546A/L754A mutant | x-ray diffraction | A | — | — |
| 4WHA | Lipoxygenase-1 (soybean) L546A/L754A mutant | x-ray diffraction | A | — | — |
| 5EEO | soybean lipoxygenase(L1)-T756R | x-ray diffraction | A | FE2 | — |
| 5EEO | Soybean LIPOXYGENASE(L1)-T756R | x-ray diffraction | A | — | — |
| 5T5V | Lipoxygenase-1 (soybean) at 293K | x-ray diffraction | A, B | FE | — |
| 5TQN | Lipoxygenase-1 (soybean) L546A mutant at 293K | x-ray diffraction | A, B | FE2 | — |
| 5TQN | Lipoxygenase-1 (soybean) L546A mutant at 293K | x-ray diffraction | A, B | FE2 | — |
| 5TQO | Lipoxygenase-1 (soybean) L546A/L754A mutant at 300K | x-ray diffraction | A, B | FE | 20 (best 0.83) |
| 5TQO | Lipoxygenase-1 (soybean) L546A/L754A mutant at 300K | x-ray diffraction | A, B | FE | — |
| 5TQP | Lipoxygenase-1 (soybean) I553G mutant at 300K | x-ray diffraction | A, B | FE | — |
| 5TQP | Lipoxygenase-1 (soybean) I553G mutant at 300K | x-ray diffraction | A, B | FE | — |
| 5TR0 | Lipoxygenase-1 (soybean) L754A mutant at 293K | x-ray diffraction | A, B | FE2 | — |
| P08170 | AlphaFold monomer V2.0 prediction for seed linoleate 13S-lipoxygenase-1 (P08170) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4WFO chain A against the predicted model P08170: TM-score 1.00, RMSD 0.20 Å
- 4WFO chain A against the predicted model P08170: TM-score 1.00, RMSD 0.20 Å
- 5EEO chain A against the predicted model P08170: TM-score 1.00, RMSD 0.38 Å
- 5EEO chain A against the predicted model P08170: TM-score 1.00, RMSD 0.38 Å
- 3BNB chain A against the predicted model P08170: TM-score 1.00, RMSD 0.40 Å
- 3BNB chain A against the predicted model P08170: TM-score 1.00, RMSD 0.40 Å
- 1FGT chain A against the predicted model P08170: TM-score 1.00, RMSD 0.40 Å
- 1FGT chain A against the predicted model P08170: TM-score 1.00, RMSD 0.40 Å
- 1Y4K chain A against the predicted model P08170: TM-score 1.00, RMSD 0.42 Å
- 1Y4K chain A against the predicted model P08170: TM-score 1.00, RMSD 0.42 Å
Elsewhere
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