MolNFT v1 · #117650 · protein

Soybean LIPOXYGENASE(L1)-T756R

5EEO · Seed linoleate 13S-lipoxygenase-1: “Soybean LIPOXYGENASE(L1)-T756R”. X-ray diffraction, 1 ligand (FE2), 10 pockets (best druggability 0.83). MolNFT v1 #117650 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5EEO
Type: protein
Length: 806 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Seed linoleate 13S-lipoxygenase-1
EC: 1.13.11.12
UniProt: P08170
Ligands: FE2
Pockets: 10 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Seed linoleate 13S-lipoxygenase-1 (EC 1.13.11.12)	protein	806	43% helix, 15% strand	P08170

Ligands and binding sites

FE2 · Fe (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	568	0.83	0.89	58	empty
2	375	0.69	0.81	45	empty
3	217	0.48	0.75	33	empty
4	193	0.48	0.76	24	empty
5	94	0.38	0.76	18	empty

Compared structures

5EEO · soybean lipoxygenase(L1)-T756R · the same entry in another collection · chain A against A, TM-score 1.00
P08170 · AlphaFold monomer V2.0 prediction for seed linoleate 13S-lipoxygenase-1 (P08170) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08170
Elsewhere: RCSB PDB 5EEO · PDBe 5EEO · UniProt P08170

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