UniProt P04050
DNA-directed RNA polymerase II subunit RPB1 (P04050)
DNA-directed RNA polymerase II subunit RPB1 (UniProt P04050), EC 2.7.7.6: 319 experimental structures on GenesisL1, 12 ligands bound, 478 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P04050
- Protein
- DNA-directed RNA polymerase II subunit RPB1
- EC
- 2.7.7.6
- Experimental structures
- 319
- Predicted models
- 0
- Ligands
- 12
- Pockets
- 478 · 38 records with a druggable one
Structures
319 records of P04050 in the MolNFT archive: 319 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1I3Q | RNA polymerase II crystal form I at 3.1 a resolution | x-ray diffraction | A | — | — |
| 1I3Q | RNA polymerase II crystal form I at 3.1 a resolution | x-ray diffraction | A | — | — |
| 1I50 | RNA polymerase II crystal form II at 2.8 a resolution | x-ray diffraction | A | — | — |
| 1I50 | RNA polymerase II crystal form II at 2.8 a resolution | x-ray diffraction | A | — | — |
| 1I6H | RNA polymerase II elongation complex | x-ray diffraction | A | — | — |
| 1I6H | RNA polymerase II elongation complex | x-ray diffraction | A | — | — |
| 1K83 | Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin | x-ray diffraction | A | — | — |
| 1K83 | Crystal structure of yeast RNA polymerase II complexed with the inhibitor alpha amanitin | x-ray diffraction | A | — | — |
| 1NIK | Wild Type RNA Polymerase II | x-ray diffraction | A | — | — |
| 1NIK | Wild type RNA polymerase II | x-ray diffraction | A | — | — |
| 1NT9 | Complete 12-subunit RNA polymerase II | x-ray diffraction | A | — | — |
| 1NT9 | Complete 12-subunit RNA polymerase II | x-ray diffraction | A | — | — |
| 1PQV | RNA polymerase II-TFIIS complex | x-ray diffraction | A | — | — |
| 1PQV | RNA polymerase II-tfiis complex | x-ray diffraction | A | — | — |
| 1R5U | RNA polymerase II tfiib complex | x-ray diffraction | A | — | — |
| 1R5U | RNA polymerase II tfiib complex | x-ray diffraction | A | — | — |
| 1R9S | RNA polymerase II strand separated elongation complex, matched nucleotide | x-ray diffraction | A | — | — |
| 1R9S | RNA polymerase II strand separated elongation complex, matched nucleotide | x-ray diffraction | A | — | — |
| 1R9T | RNA polymerase II strand separated elongation complex, mismatched nucleotide | x-ray diffraction | A | — | — |
| 1R9T | RNA polymerase II strand separated elongation complex, mismatched nucleotide | x-ray diffraction | A | — | — |
| 1SFO | RNA polymerase II strand separated elongation complex | x-ray diffraction | A | — | — |
| 1SFO | RNA polymerase II strand separated elongation complex | x-ray diffraction | A | — | — |
| 1TWA | RNA polymerase II complexed with ATP | x-ray diffraction | A | — | — |
| 1TWA | RNA polymerase II complexed with ATP | x-ray diffraction | A | — | — |
| 1TWC | RNA polymerase II complexed with GTP | x-ray diffraction | A | — | — |
| 1TWC | RNA polymerase II complexed with GTP | x-ray diffraction | A | — | — |
| 1TWF | RNA polymerase II complexed with UTP at 2.3 A resolution | x-ray diffraction | A | — | — |
| 1TWF | RNA polymerase II complexed with UTP at 2.3 a resolution | x-ray diffraction | A | — | — |
| 1TWG | RNA polymerase II complexed with CTP | x-ray diffraction | A | — | — |
| 1TWG | RNA polymerase II complexed with CTP | x-ray diffraction | A | — | — |
| 1TWH | RNA polymerase II complexed with 2'dATP | x-ray diffraction | A | — | — |
| 1TWH | RNA polymerase II complexed with 2'DATP | x-ray diffraction | A | — | — |
| 1WCM | Complete 12-Subunit RNA Polymerase II at 3.8 Angstrom | x-ray diffraction | A | — | — |
| 1WCM | Complete 12-subunit RNA polymerase II at 3.8 ang | x-ray diffraction | A | — | — |
| 1Y1V | Refined RNA Polymerase II-TFIIS complex | x-ray diffraction | A | — | — |
| 1Y1V | Refined RNA polymerase II-tfiis complex | x-ray diffraction | A | — | — |
| 1Y1W | Complete RNA Polymerase II elongation complex | x-ray diffraction | A | — | — |
| 1Y1W | Complete RNA polymerase II elongation complex | x-ray diffraction | A | — | — |
| 1Y1Y | RNA Polymerase II-TFIIS-DNA/RNA complex | x-ray diffraction | A | — | — |
| 1Y1Y | RNA polymerase II-tfiis-DNA/RNA complex | x-ray diffraction | A | — | — |
| 1Y77 | Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP | x-ray diffraction | A | — | — |
| 1Y77 | Complete RNA polymerase II elongation complex with substrate analogue gmpcpp | x-ray diffraction | A | — | — |
| 2B63 | Complete RNA Polymerase II-RNA inhibitor complex | x-ray diffraction | A | — | — |
| 2B63 | Complete RNA polymerase II-RNA inhibitor complex | x-ray diffraction | A | — | — |
| 2B8K | 12-subunit RNA Polymerase II | x-ray diffraction | A | — | — |
| 2B8K | 12-subunit RNA polymerase II | x-ray diffraction | A | — | — |
| 2E2H | RNA polymerase II elongation complex at 5 mM Mg2+ with GTP | x-ray diffraction | A | — | — |
| 2E2H | RNA polymerase II elongation complex at 5 mm MG2+ with GTP | x-ray diffraction | A | — | — |
| 2E2I | RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP | x-ray diffraction | A | — | — |
| 2E2I | RNA polymerase II elongation complex in 5 mm MG+2 with 2'- dgtp | x-ray diffraction | A | — | — |
| 2E2J | RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP | x-ray diffraction | A | — | — |
| 2E2J | RNA polymerase II elongation complex in 5 mm MG+2 with gmpcpp | x-ray diffraction | A | — | — |
| 2JA5 | CPD lesion containing RNA Polymerase II elongation complex A | x-ray diffraction | A | — | — |
| 2JA5 | Cpd lesion containing RNA polymerase II elongation complex a | x-ray diffraction | A | — | — |
| 2JA6 | CPD lesion containing RNA Polymerase II elongation complex B | x-ray diffraction | A | — | — |
| 2JA6 | Cpd lesion containing RNA polymerase II elongation complex B | x-ray diffraction | A | — | — |
| 2JA7 | CPD lesion containing RNA Polymerase II elongation complex C | x-ray diffraction | A, M | — | — |
| 2JA7 | Cpd lesion containing RNA polymerase II elongation complex C | x-ray diffraction | A, M | — | — |
| 2JA8 | CPD lesion containing RNA Polymerase II elongation complex D | x-ray diffraction | A | — | — |
| 2JA8 | Cpd lesion containing RNA polymerase II elongation complex D | x-ray diffraction | A | — | — |
259 records more on the page itself.
Ligands
- ZN · Zinc ion · in 90 records
- MG · Magnesium ion · in 85 records
- 5N0 · 3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[(1-methyl-4-{[1-methyl-4-({1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-carbonyl) amino]butanoyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-pyrrole-2-carbonyl}amino)-1-methyl-1H-pyrrole-2-carbonyl]amino}propyl)(methyl) amino]propyl}carbamoyl)benzoic acid · in 8 records
- 2KH · 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine · in 4 records
- APC · Diphosphomethylphosphonic acid adenosyl ester · in 4 records
- PPV · Pyrophosphate · in 4 records
- WCG · (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol · in 2 records
- AHW · 2-ethyl-7-methoxy-naphthalene · in 1 record
- ATP · Adenosine-5'-triphosphate · in 1 record
- MN · Manganese (II) ion · in 1 record
- POP · Pyrophosphate 2- · in 1 record
- WC4 · (1S)-1,4-anhydro-1-(3-methoxynaphthalen-2-yl)-5-O-phosphono-D-ribitol · in 1 record
Elsewhere
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