UniProt P00509
Aspartate aminotransferase (P00509)
Aspartate aminotransferase (UniProt P00509), EC 2.6.1.1: 178 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P00509
- Protein
- Aspartate aminotransferase
- EC
- 2.6.1.1
- Experimental structures
- 178
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 21 · 2 records with a druggable one
Structures
179 records of P00509 in the MolNFT archive: 178 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AAM | The structural basis for the altered substrate specificity of the R292D active site mutant of… | x-ray diffraction | A | — | — |
| 1AAM | The structural basis for the altered substrate specificity of the R292D active site mutant of… | x-ray diffraction | A | — | — |
| 1AAW | The structural basis for the altered substrate specificity of the R292D active site mutant of… | x-ray diffraction | A | — | — |
| 1AAW | The structural basis for the altered substrate specificity of the R292D active site mutant of… | x-ray diffraction | A | — | — |
| 1AHE | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHE | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHF | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHF | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHG | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHG | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHX | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHX | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHY | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AHY | Aspartate aminotransferase hexamutant | x-ray diffraction | A, B | — | — |
| 1AIA | Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the… | x-ray diffraction | A, B | — | — |
| 1AIA | Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the… | x-ray diffraction | A, B | — | — |
| 1AIB | Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the… | x-ray diffraction | A, B | — | — |
| 1AIB | Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the… | x-ray diffraction | A, B | — | — |
| 1AIC | Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the… | x-ray diffraction | A, B | — | — |
| 1AIC | Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the… | x-ray diffraction | A, B | — | — |
| 1AMQ | X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1AMQ | X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1AMR | X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1AMR | X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1AMS | X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1AMS | X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1ARG | Aspartate aminotransferase, phospho-5'-pyridoxyl aspartate complex | x-ray diffraction | A, B | — | — |
| 1ARG | Aspartate aminotransferase, phospho-5'-pyridoxyl aspartate complex | x-ray diffraction | A, B | — | — |
| 1ARH | Aspartate aminotransferase, Y225R/R386A mutant | x-ray diffraction | A, B | — | — |
| 1ARH | Aspartate aminotransferase, Y225R/R386A mutant | x-ray diffraction | A, B | — | — |
| 1ARI | Aspartate aminotransferase, W140H mutant, maleate complex | x-ray diffraction | A, B | — | — |
| 1ARI | Aspartate aminotransferase, W140H mutant, maleate complex | x-ray diffraction | A, B | — | — |
| 1ARS | X-ray crystallographic study of pyridoxal 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1ARS | X-ray crystallographic study of pyridoxal 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1ART | X-ray crystallographic study of pyridoxal 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1ART | X-ray crystallographic study of pyridoxal 5'-phosphate-type aspartate aminotransferases from… | x-ray diffraction | A | — | — |
| 1ASA | The structural basis for the reduced activity of the Y226F(Y225F) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASA | The structural basis for the reduced activity of the Y226F(Y225F) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASB | The structural basis for the reduced activity of the D223A(D222A) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASB | The structural basis for the reduced activity of the D223A(D222A) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASC | The structural basis for the reduced activity of the D223A(D222A) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASC | The structural basis for the reduced activity of the D223A(D222A) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASD | The structure of wild type E. COLI aspartate aminotransferase reconstituted with N-meplp | x-ray diffraction | A | — | — |
| 1ASD | The structure of wild type E. COLI aspartate aminotransferase reconstituted with N-meplp | x-ray diffraction | A | — | — |
| 1ASE | The structure of wild type E. COLI aspartate aminotransferase reconstituted with plp-N-oxide | x-ray diffraction | A | — | — |
| 1ASE | The structure of wild type E. COLI aspartate aminotransferase reconstituted with plp-N-oxide | x-ray diffraction | A | — | — |
| 1ASF | The structural basis for the reduced activity of the Y226F(Y225F) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASF | The structural basis for the reduced activity of the Y226F(Y225F) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASG | The structural basis for the reduced activity of the Y226F(Y225F) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASG | The structural basis for the reduced activity of the Y226F(Y225F) active site mutant of E. COLI… | x-ray diffraction | A | — | — |
| 1ASL | Crystal structures of escherichia COLI aspartate aminotransferase in two conformations: comparison… | x-ray diffraction | A, B | — | — |
| 1ASL | Crystal structures of escherichia COLI aspartate aminotransferase in two conformations: comparison… | x-ray diffraction | A, B | — | — |
| 1ASM | Crystal structures of escherichia COLI aspartate aminotransferase in two conformations: comparison… | x-ray diffraction | A, B | — | — |
| 1ASM | Crystal structures of escherichia COLI aspartate aminotransferase in two conformations: comparison… | x-ray diffraction | A, B | — | — |
| 1ASN | Crystal structures of escherichia COLI aspartate aminotransferase in two conformations: comparison… | x-ray diffraction | A, B | — | — |
| 1ASN | Crystal structures of escherichia COLI aspartate aminotransferase in two conformations: comparison… | x-ray diffraction | A, B | — | — |
| 1B4X | Aspartate aminotransferase from E. COLI, C191S mutation, with bound maleate | x-ray diffraction | A | — | — |
| 1B4X | Aspartate aminotransferase from E. COLI, C191S mutation, with bound maleate | x-ray diffraction | A | — | — |
| 1BQA | Aspartate aminotransferase P195A mutant | x-ray diffraction | A, B | — | — |
| 1BQA | Aspartate aminotransferase P195A mutant | x-ray diffraction | A, B | — | — |
119 records more on the page itself.
Ligands
Experiment against prediction
- 1ARH chain B against the predicted model P00509: TM-score 0.99, RMSD 0.37 Å
- 1IX7 chain A against the predicted model P00509: TM-score 1.00, RMSD 0.40 Å
- 1IX7 chain A against the predicted model P00509: TM-score 1.00, RMSD 0.40 Å
- 3ZZK chain A against the predicted model P00509: TM-score 1.00, RMSD 0.42 Å
- 3ZZK chain A against the predicted model P00509: TM-score 1.00, RMSD 0.42 Å
- 1ARH chain A against the predicted model P00509: TM-score 0.99, RMSD 0.42 Å
- 1ARH chain A against the predicted model P00509: TM-score 0.99, RMSD 0.42 Å
- 1CQ6 chain A against the predicted model P00509: TM-score 0.99, RMSD 0.45 Å
- 1CQ6 chain A against the predicted model P00509: TM-score 0.99, RMSD 0.45 Å
- 1AIB chain B against the predicted model P00509: TM-score 1.00, RMSD 0.45 Å
Elsewhere
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