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Ligand · PLA

PLA · 2-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl)-amino]-2-methyl-succinic acid

PLA, 2-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl)-amino]-2-methyl-succinic acid (C13 H19 N2 O9 P, 378.3 g/mol), in the MolNFT structures on GenesisL1: bound in 15 records (8 PDB entries). Every binding site with its…

Component
PLA
Formula
C13 H19 N2 O9 P
Class
ligand
Structures
15
PDB entries
8

Binding sites

PLA in 15 structures; the first of them:

  • 1AJS · Refinement and comparison of the crystal structures of pig cytosolic aspartate… · PLA A415 · binds VAL17, PHE18, VAL37, GLY38, LEU106, GLY107, GLY108, THR109 and 17 more
  • 1AMA · Domain closure in mitochondrial aspartate aminotransferase · PLA A411 · binds ILE17, LEU18, VAL37, GLY38, SER107, GLY108, THR109, LEU112 and 13 more
  • 1ASL · Crystal structures of escherichia COLI aspartate aminotransferase in two conformations… · PLA A410 · binds ILE17, LEU18, ILE37, GLY38, GLY107, GLY108, THR109, TRP140 and 14 more
  • 1FE1 · Crystal structure photosystem II · PLA B180 · binds UNK139
  • 1IZL · Crystal Structure of Photosystem II · PLA D358 · binds ILE213, HIS214, THR217, PHE257, LYS264
  • 1TAS · Crystalline mitochondrial aspartate aminotransferase exists in only two conformations · PLA A411 · binds ILE17, LEU18, GLY36, VAL37, GLY38, SER107, GLY108, THR109 and 17 more
  • 5VJZ · Joint X-ray/neutron structure of aspartate aminotransferase with alpha-methyl-aspartate… · PLA A501 · binds VAL17, PHE18, VAL37, GLY38, LEU106, GLY107, GLY108, THR109 and 15 more
  • 7TUR · Joint X-ray/neutron structure of aspastate aminotransferase (AAT) in complex with… · PLA A2001 · binds VAL17, PHE18, VAL37, GLY38, GLY107, GLY108, THR109, TRP140 and 14 more
  • 1AJS · Refinement and comparison of the crystal structures of pig cytosolic aspartate… · PLA A415 · binds VAL17, PHE18, VAL37, GLY38, LEU106, GLY107, GLY108, THR109 and 17 more
  • 1AMA · Domain closure in mitochondrial aspartate aminotransferase · PLA A411 · binds ILE17, LEU18, VAL37, GLY38, SER107, GLY108, THR109, LEU112 and 13 more
  • 1ASL · Crystal structures of escherichia COLI aspartate aminotransferase in two conformations… · PLA A410 · binds ILE17, LEU18, ILE37, GLY38, GLY107, GLY108, THR109, TRP140 and 14 more
  • 1FE1 · Crystal structure photosystem II · PLA B180 · binds UNK139
  • 1IZL · Crystal structure of photosystem II · PLA D358 · binds ILE213, HIS214, THR217, PHE257, LYS264
  • 1TAS · Crystalline mitochondrial aspartate aminotransferase exists in only two conformations · PLA A411 · binds ILE17, LEU18, GLY36, VAL37, GLY38, SER107, GLY108, THR109 and 17 more
  • 5VJZ · Joint X-RAY/NEUTRON structure of aspartate aminotransferase with alpha-methyl-aspartate… · PLA A501 · binds VAL17, PHE18, VAL37, GLY38, LEU106, GLY107, GLY108, THR109 and 15 more

Residues it binds most

ARG 15, GLY 15, SER 15, TYR 15, HIS 19, PHE 19, ALA 15, ILE 14, LEU 14, LYS 19 (residue and the binding sites it lines).

Found with

  • CLA · Chlorophyll A
  • HEM · Protoporphyrin IX containing Fe
  • PHO · Pheophytin A
  • FE · Fe (III) ion
  • MN · Manganese (II) ion
  • BCR · Beta-carotene
  • TYR · Tyrosine
  • CD · Cadmium ion
  • PMP · 4'-deoxy-4'-aminopyridoxal-5'-phosphate

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