UniProt O76290
Pteridine reductase (O76290)
Pteridine reductase (UniProt O76290): 111 experimental structures on GenesisL1, 24 ligands bound, 7 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O76290
- Protein
- Pteridine reductase
- Experimental structures
- 111
- Predicted models
- 0
- Ligands
- 24
- Pockets
- 7 · 1 record with a druggable one
Structures
111 records of O76290 in the MolNFT archive: 111 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2C7V | Structure of Trypanosoma brucei pteridine reductase (PTR1) in ternary complex with cofactor and the… | x-ray diffraction | A, B, C, D | — | — |
| 2C7V | Structure of trypanosoma brucei pteridine reductase (PTR1) in ternary complex with cofactor and the… | x-ray diffraction | A, B, C, D | — | — |
| 2VZ0 | Pteridine Reductase 1 (PTR1) from Trypanosoma Brucei in complex with NADP and DDD00066641 | x-ray diffraction | A, B, C, D | — | — |
| 2VZ0 | Pteridine reductase 1 (PTR1) from trypanosoma brucei in complex with NADP and DDD00066641 | x-ray diffraction | A, B, C, D | — | — |
| 2WD7 | Pteridine reductase 1 (PTR1) from trypanosoma brucei in complex with NADP and DDD00066750 | x-ray diffraction | A, B, C, D | — | — |
| 2WD7 | Pteridine reductase 1 (PTR1) from trypanosoma brucei in complex with NADP and DDD00066750 | x-ray diffraction | A, B, C, D | — | — |
| 2WD8 | Pteridine reductase 1 (PTR1) from trypanosoma brucei in complex with NADP and DDD00071204 | x-ray diffraction | A, B, C, D | — | — |
| 2WD8 | Pteridine reductase 1 (PTR1) from trypanosoma brucei in complex with NADP and DDD00071204 | x-ray diffraction | A, B, C, D | — | — |
| 2X9G | High resolution structure of TbPTR1 in complex with Pemetrexed | x-ray diffraction | A, B, C, D | — | — |
| 2X9G | High resolution structure of TBPTR1 in complex with pemetrexed | x-ray diffraction | A, B, C, D | — | — |
| 2X9N | High resolution structure of TbPTR1 in complex with cyromazine | x-ray diffraction | A, B, C, D | — | — |
| 2X9N | High resolution structure of TBPTR1 in complex with cyromazine | x-ray diffraction | A, B, C, D | — | — |
| 2X9V | High resolution structure of TbPTR1 with trimetrexate | x-ray diffraction | A, B, C, D | — | — |
| 2X9V | High resolution structure of TBPTR1 with trimetrexate | x-ray diffraction | A, B, C, D | — | — |
| 2YHU | Trypanosoma brucei PTR1 in complex with inhibitor WHF30 | x-ray diffraction | A, B, C, D | — | — |
| 2YHU | Trypanosoma brucei PTR1 in complex with inhibitor WHF30 | x-ray diffraction | A, B, C, D | — | — |
| 3BMC | Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3BMC | Structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3BMN | Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3BMN | Structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3BMO | Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3BMO | Structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3BMQ | Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3BMQ | Structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3GN1 | Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3GN1 | Structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3GN2 | Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3GN2 | Structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with cofactor… | x-ray diffraction | A, B, C, D | — | — |
| 3MCV | Structure of PTR1 from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 3MCV | Structure of PTR1 from trypanosoma brucei in ternary complex with 2,4… | x-ray diffraction | A, B, C, D | — | — |
| 4CL8 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CL8 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLD | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLD | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLE | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLE | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLH | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLH | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLO | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLO | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLR | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLR | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLX | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CLX | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM1 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM1 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM3 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM3 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM4 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM4 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM5 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM5 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM6 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM6 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM7 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM7 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM8 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM8 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM9 | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4CM9 | Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary complex with… | x-ray diffraction | A, B, C, D | — | — |
51 records more on the page itself.
Ligands
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · in 25 records
- 1CY · 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine · in 2 records
- EUH · 6-(trifluoromethylsulfanyl)-1,3-benzothiazol-2-amine · in 2 records
- GFE · 1-(3,4-dichlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine · in 2 records
- GJQ · (2~{R})-1-(3,4-dichlorophenyl)-2-(4-nitrophenyl)-2~{H}-1,3,5-triazine-4,6-diamine · in 2 records
- 6F4 · N~2~-[(thiophen-2-yl)methyl]-1,3,4-thiadiazole-2,5-diamine · in 1 record
- 6KT · 2-amino-1,3-benzothiazole-6-carboxamide · in 1 record
- 6QT · (2~{R})-2-(3-hydroxyphenyl)-6-oxidanyl-2,3-dihydrochromen-4-one · in 1 record
- A1H0T · 1-[4,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]guanidine · in 1 record
- CC6 · 3,5,7-trihydroxy-2-(2-hydroxyphenyl)-4H-1-benzopyran-4-one · in 1 record
- CP6 · 5-(4-chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine · in 1 record
- EUB · 4-[(2-azanyl-1,3-benzothiazol-6-yl) oxymethyl]benzenecarbonitrile · in 1 record
- EUE · 6-methylsulfonyl-1,3-benzothiazol-2-amine · in 1 record
- EUK · 6-[(3,4-dichlorophenyl)methylsulfanyl]-1,3-benzothiazol-2-amine · in 1 record
- EV8 · Methyl 1-[4-[[(2-azanyl-1,3-benzothiazol-6-yl) carbonylamino]methyl]phenyl]carbonylpiperidine-4-carboxylate · in 1 record
- EVW · 2-azanyl-~{N}-(diphenylmethyl)-1,3-benzothiazole-6-carboxamide · in 1 record
- EVZ · Methyl 1-[4-[(2-azanyl-1,3-benzothiazol-6-yl) sulfanylmethyl]phenyl]carbonylpiperidine-4-carboxylate · in 1 record
- EWK · 4-[(2-azanyl-1,3-benzothiazol-6-yl)sulfanylmethyl]-~{N}-(phenylmethyl)benzamide · in 1 record
- EWT · 2-azanyl-~{N}-[(3,4-dichlorophenyl)methyl]-1,3-benzothiazole-6-carboxamide · in 1 record
- FE1 · Methyl 1-(4-{[(2,4-diaminopteridin-6-yl) methyl](methyl)amino}benzoyl)piperidine-4-carboxylate · in 1 record
- KM5 · Methyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-ethyl-amino]phenyl]carbonylpiperidine-4-carboxylate · in 1 record
- KMK · Methyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-(3-oxidanylpropyl)amino]phenyl]carbonylpiperidine-4-carboxylate · in 1 record
- N0Z · 2,4-bis(azanyl)-9~{H}-pyrimido[4,5-b]indol-6-ol · in 1 record
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 1 record
Elsewhere
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