GL1X · GenesisL1 explorer

Ligand · JR2

JR2 · 4-(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

JR2, 4-(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (C10 H13 N5, 203.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
JR2
Formula
C10 H13 N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

JR2 in 2 structures; the first of them:

  • 4CLE · Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary… · JR2 A1270 · binds ARG14, SER95, ALA96, PHE97, ASP161, TYR174, PRO210
  • 4CLE · Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary… · JR2 A1270 · binds ARG14, SER95, ALA96, PHE97, ASP161, TYR174, PRO210

Residues it binds most

PHE 12, ASP 12, LEU 8, PRO 12, TYR 12, ALA 8, ARG 8, SER 8, MET 4, CYS 4 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • DTD · Dithiane diol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.