UniProt O57947
Ribose 1,5-bisphosphate isomerase (O57947)
Ribose 1,5-bisphosphate isomerase (UniProt O57947), EC 5.3.1.29: 26 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 107 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O57947
- Protein
- Ribose 1,5-bisphosphate isomerase
- EC
- 5.3.1.29
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 107 · 10 records with a druggable one
Structures
27 records of O57947 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5YFJ | Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex… | x-ray diffraction | A, B, C | RUB, K, CL | 11 (best 0.77) |
| 5YFJ | Crystal structure of ribose-1,5-bisphosphate isomerase from pyrococcus horikoshii OT3 in complex… | x-ray diffraction | A, B, C | RUB, K, CL | — |
| 5YFS | Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from Pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, K, CL | — |
| 5YFS | Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, K, CL | — |
| 5YFT | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from Pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, K, CL | 11 (best 0.76) |
| 5YFT | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, K, CL | — |
| 5YFU | Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex… | x-ray diffraction | A, B, C | RUB, K, AMP | 11 (best 0.77) |
| 5YFU | Crystal structure of ribose-1,5-bisphosphate isomerase from pyrococcus horikoshii OT3 in complex… | x-ray diffraction | A, B, C | RUB, K, AMP | — |
| 5YFV | Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from Pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, AMP, K | — |
| 5YFV | Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, AMP, K | — |
| 5YFW | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from Pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, AMP, K | 10 (best 0.79) |
| 5YFW | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, AMP, K | — |
| 5YFX | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from Pyrococcus horikoshii OT3… | x-ray diffraction | A | RI2, AMP | — |
| 5YFX | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from pyrococcus horikoshii OT3… | x-ray diffraction | A | RI2, AMP | — |
| 5YG5 | Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex… | x-ray diffraction | A, B, C | RUB, K, 5GP | 13 (best 0.79) |
| 5YG5 | Crystal structure of ribose-1,5-bisphosphate isomerase from pyrococcus horikoshii OT3 in complex… | x-ray diffraction | A, B, C | RUB, K, G | — |
| 5YG6 | Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from Pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, K, 5GP | — |
| 5YG6 | Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, K, G | — |
| 5YG7 | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from Pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, K, 5GP | 13 (best 0.75) |
| 5YG7 | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, K, G | — |
| 5YG8 | Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex… | x-ray diffraction | A, B, C | RUB, AMP, K, 5GP | 14 (best 0.72) |
| 5YG8 | Crystal structure of ribose-1,5-bisphosphate isomerase from pyrococcus horikoshii OT3 in complex… | x-ray diffraction | A, B, C | RUB, AMP, K, G | — |
| 5YG9 | Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from Pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, AMP, K, 5GP | 10 (best 0.77) |
| 5YG9 | Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, AMP, K, G | — |
| 5YGA | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from Pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, AMP, K, 5GP | 11 (best 0.77) |
| 5YGA | Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from pyrococcus horikoshii OT3… | x-ray diffraction | A, B, C | RI2, AMP, K, G | — |
| O57947 | AlphaFold monomer V2.0 prediction for ribose 1,5-bisphosphate isomerase (O57947) | predicted | A | — | 3 (best 0.72) |
Ligands
- K · Potassium ion · in 24 records
- RI2 · 1,5-di-O-phosphono-alpha-D-ribofuranose · in 18 records
- AMP · Adenosine monophosphate · in 14 records
- RUB · Ribulose-1,5-diphosphate · in 8 records
- 5GP · Guanosine-5'-monophosphate · in 6 records
- CL · Chloride ion · in 6 records
- G · Guanosine-5'-monophosphate · in 6 records
Experiment against prediction
- 5YG7 chain A against the predicted model O57947: TM-score 0.97, RMSD 1.12 Å
- 5YG7 chain A against the predicted model O57947: TM-score 0.97, RMSD 1.12 Å
- 5YFT chain A against the predicted model O57947: TM-score 0.97, RMSD 1.13 Å
- 5YFT chain A against the predicted model O57947: TM-score 0.97, RMSD 1.13 Å
- 5YFW chain A against the predicted model O57947: TM-score 0.97, RMSD 1.14 Å
- 5YFW chain A against the predicted model O57947: TM-score 0.97, RMSD 1.14 Å
- 5YG9 chain A against the predicted model O57947: TM-score 0.97, RMSD 1.14 Å
- 5YG9 chain A against the predicted model O57947: TM-score 0.97, RMSD 1.14 Å
- 5YG7 chain C against the predicted model O57947: TM-score 0.97, RMSD 1.14 Å
- 5YG7 chain B against the predicted model O57947: TM-score 0.97, RMSD 1.15 Å
Elsewhere
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