UniProt O14561
Acyl carrier protein, mitochondrial (O14561)
Acyl carrier protein, mitochondrial (UniProt O14561): 27 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14561
- Protein
- Acyl carrier protein, mitochondrial
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 5 · 3 records with a druggable one
Structures
28 records of O14561 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DNW | Solution structure of RSGI RUH-059, an ACP domain of acyl carrier protein, mitochondrial… | solution nmr | A | — | — |
| 2DNW | Solution structure of rsgi ruh-059, an acp domain of acyl carrier protein, mitochondrial… | solution nmr | A | — | — |
| 5OOL | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | w | PNS | — |
| 5OOL | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | w | PNS | — |
| 5OOM | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | w | PNS | — |
| 5OOM | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | w | PNS | — |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | G | 8Q1 | 1 (best 0.87) |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | G | 8Q1 | — |
| 5XTC | Cryo-EM structure of human respiratory complex I transmembrane arm | electron microscopy | X | 8Q1 | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | G, X | 8Q1 | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | G, X | 8Q1 | 2 (best 0.87) |
| 6ODD | Crystal structure of the human complex ACP-ISD11 | x-ray diffraction | A | 8Q1, CA | 2 (best 0.63) |
| 6ODD | Crystal structure of the human complex acp-ISD11 | x-ray diffraction | A | 8Q1, CA | — |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | w | — | — |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | w | — | — |
| 7OF5 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | w | — | — |
| 7OI6 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 1 | electron microscopy | w | 4S8 | — |
| 7OI7 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2 | electron microscopy | w | PNS | — |
| 7OI8 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3A | electron microscopy | w | PNS | — |
| 7OI9 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B | electron microscopy | w | PNS | — |
| 7OIC | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4 | electron microscopy | w | PNS | — |
| 7OIE | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5B | electron microscopy | w | PNS | — |
| 7PD3 | Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and… | electron microscopy | w | PNS | — |
| 7QH6 | Cryo-EM structure of the human mtlsu assembly intermediate upon MRM2 depletion - class 1 | electron microscopy | w | — | — |
| 7QH7 | Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4 | electron microscopy | w | — | — |
| 7QH7 | Cryo-EM structure of the human mtlsu assembly intermediate upon MRM2 depletion - class 4 | electron microscopy | w | — | — |
| 8PK0 | human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7 | electron microscopy | w | PM8 | — |
| O14561 | AlphaFold monomer V2.0 prediction for acyl carrier protein, mitochondrial (O14561) | predicted | A | — | — |
Ligands
- PNS · 4'-phosphopantetheine · in 10 records
- 8Q1 · S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy) butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate · in 7 records
- CA · Calcium ion · in 2 records
- 4S8 · N~3~-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-(2-sulfanylethyl)-beta-alaninamide · in 1 record
- PM8 · S-(2-{[N-(2-hydroxy-4-{[hydroxy(oxido)phosphino]oxy}-3,3-dimethylbutanoyl)-beta-alanyl]amino}ethyl) decanethioate · in 1 record
Experiment against prediction
- 6ODD chain A against the predicted model O14561: TM-score 0.97, RMSD 0.65 Å
- 6ODD chain A against the predicted model O14561: TM-score 0.97, RMSD 0.65 Å
- 5XTH chain X against the predicted model O14561: TM-score 0.96, RMSD 0.73 Å
- 5XTD chain X against the predicted model O14561: TM-score 0.96, RMSD 0.73 Å
- 5XTC chain X against the predicted model O14561: TM-score 0.96, RMSD 0.73 Å
- 7OF0 chain w against the predicted model O14561: TM-score 0.90, RMSD 1.19 Å
- 7OF0 chain w against the predicted model O14561: TM-score 0.90, RMSD 1.19 Å
- 7OF5 chain w against the predicted model O14561: TM-score 0.89, RMSD 1.22 Å
- 8PK0 chain w against the predicted model O14561: TM-score 0.89, RMSD 1.24 Å
- 5XTD chain G against the predicted model O14561: TM-score 0.88, RMSD 1.37 Å
Elsewhere
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