PM8 · S-(2-{[N-(2-hydroxy-4-{[hydroxy(oxido)phosphino]oxy}-3,3-dimethylbutanoyl)-beta-alanyl]amino}ethyl) decanethioate

Binding sites

PM8 in 8 structures; the first of them:

• 6SGA · Body domain of the mt-SSU assemblosome from Trypanosoma brucei · PM8 FcA1 · binds THR27, GLN29, GLN30, CYS32, LEU36, ARG57, VAL58, GLU61 and 13 more
• 6SGB · mt-SSU assemblosome of Trypanosoma brucei · PM8 Fc201 · binds THR27, GLN29, GLN30, LEU36, VAL58, GLU61, PHE62, TYR65 and 12 more
• 6YXX · State A of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate · PM8 ER200 · binds THR195, ASN104, SER105, LEU106, VAL3, ARG8, THR11, ARG12 and 17 more
• 6YXY · State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate · PM8 EK200 · binds ARG294, ALA297, TYR340, PRO49, ALA51, ALA54, CYS55, LEU57 and 13 more
• 7ODT · State C of the human mitoribosomal large subunit assembly intermediate · PM8 w200 · binds GLU191, LYS192, THR195, PRO3, ARG6, VAL9, LEU10, LEU16 and 13 more
• 7PUA · Middle assembly intermediate of the Trypanosoma brucei mitoribosomal small subunit · PM8 Fc201 · binds LEU750, THR27, GLN29, GLN30, LEU36, SER54, VAL58, GLU61 and 13 more
• 8PK0 · human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7 · PM8 w200 · binds GLU191, LYS192, ARG6, ILE35, GLU38, PHE39, ASN42, GLN43 and 11 more
• 8QSJ · Human mitoribosomal large subunit assembly intermediate 2 with GTPBP7 · PM8 w200 · binds GLU191, ARG6, VAL9, LEU10, LEU16, SER34, ILE35, GLU38 and 14 more

Residues it binds most

LEU 9, ARG 8, GLU 9, VAL 7, SER 9, GLN 6, PHE 9, ILE 8, ASN 8, TYR 6 (residue and the binding sites it lines).

Found with

• MG · Magnesium ion
• ZN · Zinc ion
• ATP · Adenosine-5'-triphosphate
• GTP · Guanosine-5'-triphosphate
• SAM · S-adenosylmethionine
• PO4 · Phosphate ion
• FES · Fe2/s2 (inorganic) cluster
• GDP · Guanosine-5'-diphosphate
• GNP · Phosphoaminophosphonic acid-guanylate ester
• NAD · Nicotinamide-adenine-dinucleotide
• K · Potassium ion
• NA · Sodium ion