UniProt O07347
Signal recognition particle protein (O07347)
Signal recognition particle protein (UniProt O07347): 40 experimental structures and 1 predicted model on GenesisL1, 10 ligands bound, 56 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O07347
- Protein
- Signal recognition particle protein
- Experimental structures
- 40
- Predicted models
- 1
- Ligands
- 10
- Pockets
- 56 · 7 records with a druggable one
Structures
41 records of O07347 in the MolNFT archive: 40 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FFH | N and GTPase domains of the signal sequence recognition protein ffh from thermus aquaticus | x-ray diffraction | A | MG | 3 (best 0.42) |
| 1FFH | N and GTPase domains of the signal sequence recognition protein ffh from thermus aquaticus | x-ray diffraction | A | — | — |
| 1JPJ | GMPPNP Complex of SRP GTPase NG Domain | x-ray diffraction | A | GNP | 1 (best 0.38) |
| 1JPJ | Gmppnp complex of srp GTPase ng domain | x-ray diffraction | A | — | — |
| 1JPN | GMPPNP Complex of SRP GTPase NG Domain | x-ray diffraction | B, A | CA, GNP | 13 (best 0.66) |
| 1JPN | Gmppnp complex of srp GTPase ng domain | x-ray diffraction | B, A | — | — |
| 1LS1 | T. aquaticus Ffh NG Domain at 1.1A Resolution | x-ray diffraction | A | MG, OXY | 2 (best 0.36) |
| 1LS1 | T. aquaticus ffh ng domain at 1.1A resolution | x-ray diffraction | A | — | — |
| 1NG1 | N and GTPase domains of the signal sequence recognition protein ffh from thermus aquaticus | x-ray diffraction | A | CD, MG, GDP | 3 (best 0.55) |
| 1NG1 | N and GTPase domains of the signal sequence recognition protein ffh from thermus aquaticus | x-ray diffraction | A | — | — |
| 1O87 | A new MgGDP complex of the Ffh NG domain | x-ray diffraction | A, B | CL, GDP, MG | 10 (best 0.58) |
| 1O87 | A new mggdp complex of the ffh ng domain | x-ray diffraction | A, B | — | — |
| 1OKK | Homo-heterodimeric complex of the srp gtpases | x-ray diffraction | A | GCP, MG, BZP, SO4 | 7 (best 0.82) |
| 1OKK | Homo-heterodimeric complex of the srp gtpases | x-ray diffraction | A | — | — |
| 1RJ9 | Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle… | x-ray diffraction | B | GCP, MG | 6 (best 0.83) |
| 1RJ9 | Structure of the heterodimer of the conserved GTPase domains of the signal recognition particle… | x-ray diffraction | B | — | — |
| 2C03 | GDP complex of srp GTPase ffh ng domain | x-ray diffraction | A, B | — | — |
| 2C03 | GDP complex of srp GTPase ffh ng domain | x-ray diffraction | A, B | — | — |
| 2C04 | GMPPCP complex of SRP GTPase Ffh NG Domain at ultra-high resolution | x-ray diffraction | A, B | — | — |
| 2C04 | Gmppcp complex of srp GTPase ffh ng domain at ultra-high resolution | x-ray diffraction | A, B | — | — |
| 2CNW | GDPALF4 complex of the SRP GTPases Ffh and FtsY | x-ray diffraction | A, B, C | — | — |
| 2CNW | GDPALF4 complex of the srp gtpases ffh and ftsy | x-ray diffraction | A, B, C | — | — |
| 2FFH | The signal sequence binding protein ffh from thermus aquaticus | x-ray diffraction | A, B, C | — | — |
| 2FFH | The signal sequence binding protein ffh from thermus aquaticus | x-ray diffraction | A, B, C | — | — |
| 2IY3 | Structure of the E. Coli Signal Regognition Particle | electron microscopy | A | — | — |
| 2IY3 | Structure of the E. COLI signal regognition particle | electron microscopy | A | — | — |
| 2J45 | Water structure of T. Aquaticus Ffh NG Domain At 1.1A Resolution | x-ray diffraction | A, B | — | — |
| 2J45 | Water structure of T. aquaticus ffh ng domain at 1.1A resolution | x-ray diffraction | A, B | — | — |
| 2J46 | Water structure of T. Aquaticus Ffh NG Domain At 1.1A Resolution | x-ray diffraction | A, B | — | — |
| 2J46 | Water structure of T. aquaticus ffh ng domain at 1.1A resolution | x-ray diffraction | A, B | — | — |
| 2J7P | GMPPNP-stabilized NG domain complex of the SRP GTPases Ffh and FtsY | x-ray diffraction | A, B | — | — |
| 2J7P | Gmppnp-stabilized ng domain complex of the srp gtpases ffh and ftsy | x-ray diffraction | A, B | — | — |
| 2NG1 | N and GTPase domains of the signal sequence recognition protein ffh from thermus aquaticus | x-ray diffraction | A | GDP | 4 (best 0.67) |
| 2NG1 | N and GTPase domains of the signal sequence recognition protein ffh from thermus aquaticus | x-ray diffraction | A | — | — |
| 2XKV | Atomic Model of the SRP-FtsY Early Conformation | electron microscopy | A | — | — |
| 2XKV | Atomic model of the srp-ftsy early conformation | electron microscopy | A | — | — |
| 3NG1 | N and GTPase domains of the signal sequence recognition protein ffh from thermus aquaticus | x-ray diffraction | A, B | — | — |
| 3NG1 | N and GTPase domains of the signal sequence recognition protein ffh from thermus aquaticus | x-ray diffraction | A, B | — | — |
| 3ZN8 | Structural Basis of Signal Sequence Surveillance and Selection by the SRP-SR Complex | electron microscopy | A | — | — |
| 3ZN8 | Structural basis of signal sequence surveillance and selection by the srp-sr complex | electron microscopy | A | — | — |
| O07347 | AlphaFold monomer V2.0 prediction for signal recognition particle protein (O07347) | predicted | A | — | 7 (best 0.59) |
Ligands
- MG · Magnesium ion · in 6 records
- GDP · Guanosine-5'-diphosphate · in 3 records
- GCP · Phosphomethylphosphonic acid guanylate ester · in 2 records
- GNP · Phosphoaminophosphonic acid-guanylate ester · in 2 records
- BZP · N1-carboxypiperazine · in 1 record
- CA · Calcium ion · in 1 record
- CD · Cadmium ion · in 1 record
- CL · Chloride ion · in 1 record
- OXY · Oxygen molecule · in 1 record
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 1FFH chain A against the predicted model O07347: TM-score 0.99, RMSD 0.64 Å
- 1FFH chain A against the predicted model O07347: TM-score 0.99, RMSD 0.64 Å
- 1LS1 chain A against the predicted model O07347: TM-score 0.99, RMSD 0.68 Å
- 1LS1 chain A against the predicted model O07347: TM-score 0.99, RMSD 0.68 Å
- 2NG1 chain A against the predicted model O07347: TM-score 0.99, RMSD 0.69 Å
- 2NG1 chain A against the predicted model O07347: TM-score 0.99, RMSD 0.69 Å
- 1JPN chain B against the predicted model O07347: TM-score 0.99, RMSD 0.73 Å
- 1JPN chain B against the predicted model O07347: TM-score 0.99, RMSD 0.73 Å
- 2C04 chain B against the predicted model O07347: TM-score 0.99, RMSD 0.76 Å
- 2C04 chain B against the predicted model O07347: TM-score 0.99, RMSD 0.76 Å
Elsewhere
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