UniProt O00560
Syntenin-1 (O00560)
Syntenin-1 (UniProt O00560): 35 experimental structures on GenesisL1, 15 ligands bound, 39 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O00560
- Protein
- Syntenin-1
- Experimental structures
- 35
- Predicted models
- 0
- Ligands
- 15
- Pockets
- 39 · 3 records with a druggable one
Structures
35 records of O00560 in the MolNFT archive: 35 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1N99 | Crystal structure of the PDZ tandem of human syntenin | x-ray diffraction | A, B | — | — |
| 1N99 | Crystal structure of the PDZ tandem of human syntenin | x-ray diffraction | A, B | — | — |
| 1NTE | Crystal structure analysis of the second PDZ domain of syntenin | x-ray diffraction | A | — | — |
| 1NTE | Crystal structure analysis of the second PDZ domain of syntenin | x-ray diffraction | A | — | — |
| 1OBX | Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide. | x-ray diffraction | A | — | — |
| 1OBX | Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide. | x-ray diffraction | A | — | — |
| 1OBY | Crystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide. | x-ray diffraction | A, B | — | — |
| 1OBY | Crystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide. | x-ray diffraction | A, B | — | — |
| 1OBZ | Crystal structure of the complex of the PDZ tandem of syntenin with an interleukin 5 receptor alpha… | x-ray diffraction | A, B | — | — |
| 1OBZ | Crystal structure of the complex of the PDZ tandem of syntenin with an interleukin 5 receptor alpha… | x-ray diffraction | A, B | — | — |
| 1R6J | Ultrahigh resolution Crystal Structure of syntenin PDZ2 | x-ray diffraction | A | — | — |
| 1R6J | Ultrahigh resolution crystal structure of syntenin PDZ2 | x-ray diffraction | A | — | — |
| 1V1T | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYKV peptide | x-ray diffraction | A, B | — | — |
| 1V1T | Crystal structure of the PDZ tandem of human syntenin in complex with tneykv peptide | x-ray diffraction | A, B | — | — |
| 1W9E | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFYF peptide | x-ray diffraction | A, B | — | — |
| 1W9E | Crystal structure of the PDZ tandem of human syntenin in complex with tnefyf peptide | x-ray diffraction | A, B | — | — |
| 1W9O | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide | x-ray diffraction | A, B | — | — |
| 1W9O | Crystal structure of the PDZ tandem of human syntenin in complex with tneyyv peptide | x-ray diffraction | A, B | — | — |
| 1W9Q | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFAF peptide | x-ray diffraction | A, B | — | — |
| 1W9Q | Crystal structure of the PDZ tandem of human syntenin in complex with tnefaf peptide | x-ray diffraction | A, B | — | — |
| 1YBO | Crystal structure of the PDZ tandem of human syntenin with syndecan peptide | x-ray diffraction | A, B | — | — |
| 1YBO | Crystal structure of the PDZ tandem of human syntenin with syndecan peptide | x-ray diffraction | A, B | — | — |
| 4Z33 | Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal… | x-ray diffraction | A, B | — | — |
| 4Z33 | Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the frizzled 7 C-terminal… | x-ray diffraction | A, B | — | — |
| 6R9H | Crystal structure of the PDZ tandem of syntenin in complex with fragment C58 | x-ray diffraction | A, B, C, D | PO4, JVK | — |
| 6RLC | Crystal structure of the PDZ tandem of syntenin in complex with fragment F13 | x-ray diffraction | A, B, C, D | K7Z | — |
| 7FSG | SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56772132 | x-ray diffraction | A, B, C, D | SO4, DGL, GLY, YG9, ALA | 16 (best 0.75) |
| 7FSI | SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z18197050 | x-ray diffraction | A, B, C, D | RZG, SO4 | — |
| 7FSJ | SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57744712 | x-ray diffraction | A, B, C, D | YEB, SO4 | — |
| 7FSQ | SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1429867185 | x-ray diffraction | A, B, C, D | VVP, SO4 | — |
| 7FSV | SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1454310449 | x-ray diffraction | A, B, C, D | UQS, SO4 | — |
| 7FSX | SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1328078283 | x-ray diffraction | A, B, C, D | I8A, DGL, SO4, GLY, ALA | 18 (best 0.73) |
| 7FT7 | SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57127349 | x-ray diffraction | A, B, C, D | SZB, SO4 | — |
| 8AAO | Crystal structure of the PDZ tandem of syntenin in complex with compound 95 | x-ray diffraction | A, B | LN2 | 5 (best 0.52) |
| O00560 | AlphaFold monomer V2.0 prediction for syntenin-1 (O00560) | — | — | — |
Ligands
- SO4 · Sulfate ion · in 7 records
- ALA · Alanine · in 2 records
- DGL · D-glutamic acid · in 2 records
- GLY · Glycine · in 2 records
- I8A · N-(cyclopropylmethyl)-2,2,3,3-tetramethylazetidine-1-carboxamide · in 1 record
- JVK · (2~{S})-2-[2-(4-chlorophenyl)sulfanylethanoylamino]-3-methyl-butanoic acid · in 1 record
- K7Z · (2~{S})-2-[3-(4-chlorophenyl)sulfanylpropanoylamino]-3-methyl-butanoic acid · in 1 record
- LN2 · (2~{S})-2-[[(2~{S})-3-[4-(5-ethanoyl-2-fluoranyl-phenyl)phenyl]-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)propanoyl]amino]propanoic acid · in 1 record
- PO4 · Phosphate ion · in 1 record
- RZG · methyl 4-sulfamoylbenzoate · in 1 record
- SZB · succinimide · in 1 record
- UQS · N-[(2-fluorophenyl)methyl]-1H-pyrazol-4-amine · in 1 record
- VVP · 4-methoxy-1H-indole · in 1 record
- YEB · N,N-dimethylmorpholine-4-sulfonamide · in 1 record
- YG9 · (5R)-5-[2-(4-methoxyphenyl)ethyl]-5-methylimidazolidine-2,4-dione · in 1 record
Elsewhere
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