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UniProt H6QM92

Polymerase acidic protein (H6QM92)

Polymerase acidic protein (UniProt H6QM92): 33 experimental structures on GenesisL1, 5 ligands bound, 195 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
H6QM92
Protein
Polymerase acidic protein
Experimental structures
33
Predicted models
0
Ligands
5
Pockets
195 · 14 records with a druggable one

Structures

33 records of H6QM92 in the MolNFT archive: 33 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4NFZCrystal structure of polymerase subunit PA N-terminal endonuclease domain from bat-derived…x-ray diffractionA, B, C——
4NFZCrystal structure of polymerase subunit pa N-terminal endonuclease domain from bat-derived…x-ray diffractionA, B, C——
4WSBBat influenza a polymerase with bound vrna promoterx-ray diffractionA——
5M3HBat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTDx-ray diffractionAZN, PO4—
5M3HBat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated pol II ctdx-ray diffractionAZN, PO4—
6EVJCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primerx-ray diffractionA, D—13 (best 0.89)
6EVJCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primerx-ray diffractionA, D——
6EVKCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and cap analogue…x-ray diffractionAZN, PO413 (best 0.84)
6EVKCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and cap analogue…x-ray diffractionAZN, PO4—
6FHHCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer…x-ray diffractionAPO4, ZN13 (best 0.88)
6FHHCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer…x-ray diffractionAPO4, ZN—
6FHICrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer…x-ray diffractionAZN, PO413 (best 0.87)
6FHICrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer…x-ray diffractionAZN, PO4—
6SZUBat Influenza A polymerase pre-termination complex with pyrophosphate using 44-mer vRNA template…electron microscopyAM4H, MG16 (best 0.90)
6SZUBat influenza a polymerase pre-termination complex with pyrophosphate using 44-mer vrna template…electron microscopyAM4H, MG—
6SZVBat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only)electron microscopyAM4H, MG15 (best 0.90)
6SZVBat influenza a polymerase elongation complex with incoming UTP analogue (core + endonuclease only)electron microscopyAM4H, MG—
6T0NBat Influenza A polymerase pre-initiation complexelectron microscopyAMG13 (best 0.86)
6T0NBat influenza a polymerase pre-initiation complexelectron microscopyA——
6T0RBat Influenza A polymerase product dissociation complex using 44-mer vRNA template with mutated…electron microscopyA—16 (best 0.80)
6T0RBat influenza a polymerase product dissociation complex using 44-mer vrna template with mutated…electron microscopyA——
6T0SBat Influenza A polymerase stuttering complex using 44-mer vRNA template with intact oligo(U)…electron microscopyA—16 (best 0.87)
6T0SBat influenza a polymerase stuttering complex using 44-mer vrna template with intact OLIGO(U)…electron microscopyA——
6T0UBat Influenza A polymerase product dissociation complex using 44-mer vRNA template with intact…electron microscopyA—17 (best 0.86)
6T0UBat influenza a polymerase product dissociation complex using 44-mer vrna template with intact…electron microscopyA——
6T0VBat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase)electron microscopyAM4H, MG—
6T0VBat influenza a polymerase elongation complex with incoming UTP analogue (complete polymerase)electron microscopyAM4H, MG—
6T2CBat Influenza A polymerase recycling complexelectron microscopyA—17 (best 0.77)
6T2CBat influenza a polymerase recycling complexelectron microscopyA——
6TW1Bat Influenza A polymerase termination complex with pyrophosphate using 44-mer vRNA template with…electron microscopyAM4H, MG13 (best 0.88)
6TW1Bat influenza a polymerase termination complex with pyrophosphate using 44-mer vrna template with…electron microscopyAM4H, MG—
9F2RInfluenza A/H17N10 polymerase with bound promoter and 3' end of template in active sitex-ray diffractionA—11 (best 0.88)
9F37Replication-like initiation state of influenza polymerase with GTP and CTP at respectively the -1…x-ray diffractionAGTP9 (best 0.89)

Ligands

  • MG · Magnesium ion · in 9 records
  • M4H · 5-oxidanyl-4-oxidanylidene-1-[(1-pyrrolo[2,3-b]pyridin-1-ylcyclopentyl)methyl]pyridine-3-carboxylic acid · in 8 records
  • PO4 · Phosphate ion · in 8 records
  • ZN · Zinc ion · in 8 records
  • GTP · Guanosine-5'-triphosphate · in 1 record

Elsewhere

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