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UniProt B3UEZ6

Envelope glycoprotein gp41 (B3UEZ6)

Envelope glycoprotein gp41 (UniProt B3UEZ6): 29 experimental structures on GenesisL1, 3 ligands bound, 70 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
B3UEZ6
Protein
Envelope glycoprotein gp41
Experimental structures
29
Predicted models
0
Ligands
3
Pockets
70 · 11 records with a druggable one

Structures

29 records of B3UEZ6 in the MolNFT archive: 29 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5VN3Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding…electron microscopyA, B, DNAG9 (best 0.75)
5VN3Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding…electron microscopyA, B, DNAG—
5VN8Cryo-EM model of B41 SOSIP.664 in complex with fragment antigen binding variable domain of b12electron microscopyA, B, CNAG6 (best 0.80)
5VN8Cryo-EM model of B41 SOSIP.664 in complex with fragment antigen binding variable domain of B12electron microscopyA, B, CNAG—
6CH9Crystal structure of a natively-glycosylated B41 SOSIP.664 HIV-1 Envelope Trimer in complex with…x-ray diffractionBNAG3 (best 0.67)
6CH9Crystal structure of a natively-glycosylated B41 SOSIP.664 HIV-1 envelope trimer in complex with…x-ray diffractionBNAG—
6EDUB41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the…electron microscopyA, B, CNAG4 (best 0.80)
6EDUB41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21C and the…electron microscopyA, B, CNAG—
6MUFCrystal Structure of HIV-1 B41 SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies…x-ray diffractionBNAG—
6MUFCrystal structure of HIV-1 B41 SOSIP.664 prefusion env trimer in complex with human antibodies…x-ray diffractionBNAG—
6MUGCrystal Structure of HIV-1 B41 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry…x-ray diffractionBNAG—
6MUGCrystal structure of HIV-1 B41 SOSIP.664 prefusion env trimer bound to small molecule HIV-1 entry…x-ray diffractionBNAG—
6OKPB41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074electron microscopyA, B, CNAG10 (best 0.81)
6OKPB41 SOSIP.664 in complex with the silent-face antibody SF12 and V3- targeting antibody 10-1074electron microscopyA, B, CNAG—
6OPNCD4- and 17-bound HIV-1 Env B41 SOSIP in complex with small molecule GO35electron microscopyB, E, HN074 (best 0.75)
6OPNCD4- and 17-bound HIV-1 env B41 sosip in complex with small molecule GO35electron microscopyB, E, HN07—
6OPOSymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDMelectron microscopyB, F, MNAG8 (best 0.78)
6OPOSymmetric model of CD4- and 17-bound B41 HIV-1 env sosip in complex with ddmelectron microscopyB, F, MNAG—
6OPPAsymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDMelectron microscopyB, E, KNAG7 (best 0.75)
6OPPAsymmetric model of CD4- and 17-bound B41 HIV-1 env sosip in complex with ddmelectron microscopyB, E, KNAG—
6OPQCD4- and 17-bound HIV-1 Env B41 SOSIP frozen with LMNGelectron microscopyB, F, G—6 (best 0.80)
6OPQCD4- and 17-bound HIV-1 env B41 sosip frozen with lmngelectron microscopyB, F, G——
6U59HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13Belectron microscopyB, D, INAG7 (best 0.86)
6U59HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13Belectron microscopyB, D, INAG—
6X5BSymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52electron microscopyB, E, KNAG, UOV6 (best 0.82)
6X5BSymmetric model of CD4- and 17-bound B41 HIV-1 env sosip in complex with small molecule GO52electron microscopyB, E, KNAG, UOV—
6X5CAsymmetric model of CD4-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52electron microscopyB, F, GUOV—
6X5CAsymmetric model of CD4-bound B41 HIV-1 env sosip in complex with small molecule GO52electron microscopyB, F, GUOV—
8D5Canti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4electron microscopyX, Y, Z——

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 22 records
  • UOV · N-(4'-methyl[1,1'-biphenyl]-4-yl)-1-oxa-7-azaspiro[3.5]nonane-7-carboxamide · in 4 records
  • N07 · [3'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-3-yl](piperidin-1-yl)methanone · in 2 records

Elsewhere

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