GL1X · GenesisL1 explorer

Ligand · S6P

S6P · D-sorbitol-6-phosphate

S6P, D-sorbitol-6-phosphate (C6 H15 O9 P, 262.1 g/mol), in the MolNFT structures on GenesisL1: bound in 42 records (21 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
S6P
Formula
C6 H15 O9 P
Class
sugar
Structures
42
PDB entries
21

Binding sites

S6P in 42 structures; the first of them:

  • 1XTB · Crystal Structure of Rabbit Phosphoglucose Isomerase Complexed with Sorbitol-6-Phosphate · S6P A2002 · binds ILE156, GLY157, GLY158, SER159, ALA208, SER209, LYS210, THR211 and 11 more
  • 2CXQ · Crystal structure of mouse AMF / S6P complex · S6P A1601 · binds ILE157, GLY158, GLY159, SER160, ALA209, SER210, LYS211, THR212 and 13 more
  • 2GC1 · The crystal structure of phosphoglucose isomerase from Pyrococcus furiosus in complex… · S6P A502 · binds ARG25, TYR52, VAL54, ALA69, THR71, THR85, LYS86, GLY87 and 9 more
  • 3CTL · Crystal structure of D-Allulose 6-Phosphate 3-Epimerase from Escherichia coli K12… · S6P A501 · binds SER6, MET8, CYS9, HIS30, ASP32, HIS63, MET65, MET135 and 14 more
  • 4KXU · Human transketolase in covalent complex with donor ketose D-fructose-6-phosphate · S6P A1014 · binds HIS37, HIS77, HIS110, GLY123, GLN189, HIS258
  • 4LY9 · Human GKRP complexed to AMG-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorphol… · S6P A713 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 11 more
  • 4MQU · Human GKRP complexed to AMG-3969 and S6P · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 10 more
  • 4MRO · Human GKRP bound to AMG-5980 and S6P · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 11 more
  • 4MSU · Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 11 more
  • 4OHK · Human GKRP bound to AMG-2526 and S6P · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 10 more
  • 4OHM · Human GKRP bound to AMG-0771 and sorbitol-6-phosphate · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 11 more
  • 4OHO · Human GKRP bound to AMG-2668 · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 12 more
  • 4OHP · Human GKRP bound to AMG-3227 and S6P · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, SER179, VAL180 and 10 more
  • 4OLH · Human GKRP Bound to AMG5106 and Sorbitol-6-Phosphate · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 11 more
  • 4OP1 · GKRP bound to AMG0556 and Sorbitol-6-Phosphate · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 12 more
  • 4OP2 · GKRP bound to AMG-0471 and Sorbitol-6-Phosphate · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, SER179, VAL180 and 11 more
  • 4OP3 · Human GKRP bound to AMG-5112 and Sorbitol-6-phosphate · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 11 more
  • 4PX2 · Human GKRP bound to AMG2882 and Sorbitol-6-Phosphate · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 12 more
  • 4PX3 · Human GKRP bound to AMG-3295 and Sorbitol-6-phosphate · S6P A702 · binds GLY107, GLY108, THR109, SER110, GLU150, GLU153, ILE178, SER179 and 10 more

Residues it binds most

SER 84, GLY 90, THR 88, GLU 76, HIS 90, ALA 88, LYS 76, ILE 80, ARG 74, VAL 70 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol
  • IOD · Iodide ion
  • SO4 · Sulfate ion
  • MG · Magnesium ion
  • 1YY · (2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol
  • 2EU · 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol
  • 2TE · (2R)-2-{4-[(2S)-4-[(6-aminopyridin-3-yl)sulfonyl]-2-(prop-1-yn-1-yl)piperazin-1-yl]phenyl}-1,1,1-trifluorohex-4-yn-2-ol
  • 2TF · (2S)-2-{4-[(2S)-4-[(6-aminopyridin-3-yl)sulfonyl]-2-(prop-1-yn-1-yl)piperazin-1-yl]phenyl}-3,3,3-trifluoropropane-1,2-diol
  • 2TG · 5-{[(3S)-3-(prop-1-yn-1-yl)-4-{4-[S-(trifluoromethyl)sulfonimidoyl]phenyl}piperazin-1-yl]sulfonyl}pyridin-2-amine
  • 2TJ · 4-[(2S)-4-[(6-aminopyridin-3-yl)sulfonyl]-2-(prop-1-yn-1-yl)piperazin-1-yl]-N-methylbenzenesulfonamide
  • 2TO · 2-(2-{4-[(6-aminopyridin-3-yl)sulfonyl]piperazin-1-yl}-3,3'-bipyridin-5-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol
  • 2UW · (2S)-2-(6-{5-[(6-aminopyridin-3-yl)sulfonyl]thiophen-2-yl}-5-chloropyridin-3-yl)-1,1,1-trifluoropropan-2-ol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.