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Ligand · 2TJ

2TJ · 4-[(2S)-4-[(6-aminopyridin-3-yl)sulfonyl]-2-(prop-1-yn-1-yl)piperazin-1-yl]-N-methylbenzenesulfonamide

2TJ, 4-[(2S)-4-[(6-aminopyridin-3-yl)sulfonyl]-2-(prop-1-yn-1-yl)piperazin-1-yl]-N-methylbenzenesulfonamide (C19 H23 N5 O4 S2, 449.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
2TJ
Formula
C19 H23 N5 O4 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

2TJ in 2 structures; the first of them:

  • 4OHP · Human GKRP bound to AMG-3227 and S6P · 2TJ A701 · binds VAL10, TYR24, GLU25, VAL28, PRO29, GLU32, LYS33, SER34 and 16 more
  • 4OHP · Human gkrp bound to amg-3227 and S6P · 2TJ A701 · binds VAL10, TYR24, GLU25, VAL28, PRO29, GLU32, LYS33, SER34 and 16 more

Residues it binds most

ARG 4, ALA 4, GLU 4, LEU 4, LYS 4, SER 4, VAL 4, ASN 4, ASP 4, GLN 4 (residue and the binding sites it lines).

Found with

  • S6P · D-sorbitol-6-phosphate
  • IOD · Iodide ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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