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Ligand · CD4

CD4 · (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate

CD4, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate (C65 H126 O17 P2, 1241.7 g/mol), in the MolNFT structures on GenesisL1: bound in 5…

Component
CD4
Formula
C65 H126 O17 P2
Class
ligand
Structures
5
PDB entries
5

Binding sites

CD4 in 5 structures; the first of them:

  • 7O0U · Cryo-EM structure (model_1a) of the RC-dLH complex from Gemmatimonas phototrophica at 2.4… · CD4 H11001 · binds PHE19, PHE20, ILE23, ILE24, ARG27, LYS31, TYR35, LEU37 and 17 more
  • 7O0V · Cryo-EM structure (model_2a) of the RC-dLH complex from Gemmatimonas phototrophica at 2.5… · CD4 H1102 · binds PHE19, PHE20, ILE23, ILE24, ARG27, LYS31, TYR35, LEU37 and 14 more
  • 7PIL · Cryo-EM structure of the Rhodobacter sphaeroides RC-LH1-PufXY monomer complex at 2.5 A · CD4 M405 · binds VAL22, PHE20, ILE22, PHE23, LEU27, TYR30, ASN199, PRO200 and 10 more
  • 7PQD · Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 A… · CD4 H302 · binds ARG15, VAL22, VAL22, ILE28, GLN32, TYR40, LEU42, ASN52 and 14 more
  • 7OY8 · Cryo-EM structure of the rhodospirillum rubrum rc-LH1 complex · CD4 H304 · binds PHE24, ARG32, ARG36, TYR40, LEU42, SER52, LEU53, GLN54 and 16 more

Residues it binds most

VAL 17, PHE 19, ARG 19, LEU 19, GLY 19, ALA 17, TRP 17, ILE 15, TYR 19, MET 12 (residue and the binding sites it lines).

Found with

  • BPH · Bacteriopheophytin A
  • FE · Fe (III) ion
  • LMT · Dodecyl-beta-D-maltoside
  • BCL · Bacteriochlorophyll A
  • CRT · Spirilloxanthin
  • PGW · (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate
  • U10 · Ubiquinone-10
  • 0V9 · (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate
  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine
  • HEC · Heme C
  • MQ8 · Menaquinone 8
  • UQ1 · Ubiquinone-1

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