PGW · (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate

Binding sites

PGW in 41 structures; the first of them:

• 6BW5 · Human GPT (DPAGT1) in complex with tunicamycin · PGW A502 · binds CYS107, PHE110, LEU111, ALA114, HIS124, LEU28, ALA31, PHE32 and 3 more
• 6TP6 · Crystal structure of the Orexin-1 receptor in complex with filorexant · PGW A411 · binds SER138, TRP145, VAL222, ALA226, GLY229, LEU230, MET233, ALA234 and 12 more
• 6TQ7 · Crystal structure of the Orexin-1 receptor in complex with SB-334867 · PGW A411 · binds SER138, VAL222, ALA226, PRO227, LEU230, MET233, ALA234, GLN237 and 11 more
• 7RX3 · afTMEM16 in C14 lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+ · PGW B801 · binds ILE210, VAL214, CYS217, SER585, TYR589, MET590, SER592, ASN593 and 8 more
• 8J8J · Membrane bound PRTase, C3 symmetry, donor bound · PGW D403 · binds ASN123, LEU126, VAL127, VAL130, MET134, CYS151, VAL152, SER154 and 21 more
• 8TPR · nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of… · PGW A803 · binds THR563, SER566, PHE567, TRP570, ARG621, HIS611, LEU614, VAL615 and 1 more
• 5TJ6 · CA2+ bound aplysia SLO1 · PGW A1109 · binds ALA112, THR137, THR138

Residues it binds most

LEU 230, VAL 163, PHE 172, ALA 121, ILE 152, TYR 158, SER 112, TRP 122, ARG 114, THR 76 (residue and the binding sites it lines).

Found with

• SOG · octyl 1-thio-beta-D-glucopyranoside
• SO4 · Sulfate ion
• PG4 · Tetraethylene glycol
• CA · Calcium ion
• K · Potassium ion
• NA · Sodium ion
• TUM · Tunicamycin
• CL · Chloride ion
• CIT · Citric acid
• CMP · Adenosine-3',5'-cyclic-monophosphate
• NT5 · [(2~{R},5~{R})-5-[(5-fluoranylpyridin-2-yl)oxymethyl]-2-methyl-piperidin-1-yl]-(5-methyl-2-pyrimidin-2-yl-phenyl)methanone
• NVK · 1-(2-methyl-1,3-benzoxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea