80Y · 2-azanylethyl [(2R,3S,4S,5S,6S)-3,4,5,6-tetrakis(oxidanyl)oxan-2-yl]methyl hydrogen phosphate

Binding sites

80Y in 4 structures; the first of them:

• 8IMX · Cryo-EM structure of GPI-T with a chimeric GPI-anchored protein · 80Y P101 · binds GLY218, THR219, THR220, ASN53, CYS206, MET1, SER2, SER3
• 8IMY · Cryo-EM structure of GPI-T (inactive mutant) with GPI and proULBP2, a proprotein substrate · 80Y G1815 · binds TYR49, SER51, GLN355, SER356, PHE357, THR220
• 8K9R · Cryo EM structure of the products-bound PGAP1(Bst1)-H443N from Chaetomium thermophilum · 80Y B101 · binds MET179, SER180, MET182, ARG238, PRO239, TRP448, THR3, SER4
• 8K9T · Cryo-EM structure of the products-bound PGAP1(Bst1)-S327A from Chaetonium thermophilum · 80Y B101 · binds MET179, SER180, MET182, ARG238, PRO239, TRP448, THR3, SER4

Residues it binds most

SER 6, THR 6, MET 3, GLN 3, ARG 2, ASN 2, GLY 2, PHE 2, PRO 2, TRP 2 (residue and the binding sites it lines).

Found with

• 05E · 2-azanylethyl [(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl] hydrogen phosphate
• PA1 · 2-amino-2-deoxy-alpha-D-glucopyranose
• 6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
• 80T · [(2R)-1-hexadecanoyloxy-3-[[3-[[(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxy-propoxy]-oxidanyl-phosphoryl]oxy-2-oxidanyl-propoxy]-oxidanyl-phosphoryl]oxy-propan-2-yl] (Z)-octadec-9-enoate
• 81Q · [(2R)-1-[[(1S,2R,3R,4S,5S,6R)-2-hexadecanoyloxy-3,4,5,6-tetrakis(oxidanyl)cyclohexyl]oxy-oxidanyl-phosphoryl]oxy-3-octadecoxy-propan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
• AJP · Digitonin
• CLR · Cholesterol
• LBN · 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
• PLM · Palmitic acid
• Y01 · Cholesterol hemisuccinate
• CA · Calcium ion
• MG · Magnesium ion