MolNFT v2 · #185150 · protein + DNA
Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state
7KZT: “Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state”. Electron microscopy at 4.2, 1 ligand (ZN). MolNFT v2 #185150 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KZT
- Type
- protein + DNA
- Length
- 11,045 residues
- Chains
- 19
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.2
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- O15360, Q8NB91, Q00597, Q9HB96, Q9NPI8, O15287, Q9NW38, Q0VG06, Q9NPD8, B7ZMF2, Q9BXW9
- Ligands
- ZN
Structure
electron microscopy · resolution 4.2 · 18 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1186 | — | O15360 |
| B | — | protein | 701 | — | Q8NB91 |
| C | — | protein | 550 | — | Q00597 |
| E | — | protein | 419 | — | Q9HB96 |
| F | — | protein | 340 | — | Q9NPI8 |
| G | — | protein | 577 | — | O15287 |
| H | — | protein | 544 | — | O15287 |
| L, M | — | protein | 370 | — | Q9NW38 |
| O | — | protein | 699 | — | Q8NB91 |
| P | — | protein | 748 | — | Q0VG06 |
| Q | — | protein | 754 | — | Q0VG06 |
| S | — | protein | 1250 | — | O15360 |
| W | — | protein | 39 | — | — |
| X | — | protein | 153 | — | Q9NPD8 |
| U | — | protein | 1181 | — | B7ZMF2 |
| V | — | protein | 1120 | — | Q9BXW9 |
| Y | — | dna | 22 | — | — |
| Z | — | dna | 22 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 5 copies · chains G, L, M
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- O15287 · AlphaFold monomer V2.0 prediction for fanconi anemia group G protein (O15287) · a predicted model of the same protein · chain H against A, TM-score 0.92
- Q00597 · AlphaFold monomer V2.0 prediction for fanconi anemia group C protein (Q00597) · a predicted model of the same protein · chain C against A, TM-score 0.88
- Q9BXW9 · AlphaFold monomer V2.0 prediction for fanconi anemia group D2 protein (Q9BXW9) · a predicted model of the same protein · chain V against A, TM-score 0.81
- O15360 · AlphaFold monomer V2.0 prediction for fanconi anemia group a protein (O15360) · a predicted model of the same protein · chain S against A, TM-score 0.75
- Q9NW38 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase fancl (Q9NW38) · a predicted model of the same protein · chain M against A, TM-score 0.71
- Q9NPI8 · AlphaFold monomer V2.0 prediction for fanconi anemia group F protein (Q9NPI8) · a predicted model of the same protein · chain F against A, TM-score 0.64
- Q0VG06 · AlphaFold monomer V2.0 prediction for fanconi anemia core complex- associated protein 100… · a predicted model of the same protein · chain P against A, TM-score 0.61
- Q9HB96 · AlphaFold monomer V2.0 prediction for fanconi anemia group E protein (Q9HB96) · a predicted model of the same protein · chain E against A, TM-score 0.58
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15360
- Every structure of UniProt Q8NB91
- Every structure of UniProt Q00597
- Every structure of UniProt Q9HB96
- Every structure of UniProt Q9NPI8
- Every structure of UniProt O15287
- Every structure of UniProt Q9NW38
- Every structure of UniProt Q0VG06
- Every structure of UniProt Q9NPD8
- Every structure of UniProt B7ZMF2
- Every structure of UniProt Q9BXW9
- Elsewhere: RCSB PDB 7KZT · PDBe 7KZT · UniProt O15360 · UniProt Q8NB91 · UniProt Q00597 · UniProt Q9HB96 · UniProt Q9NPI8 · UniProt O15287 · UniProt Q9NW38 · UniProt Q0VG06 · UniProt Q9NPD8 · UniProt B7ZMF2 · UniProt Q9BXW9
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