UniProt Q9NPD8
Ubiquitin-conjugating enzyme E2 T (Q9NPD8)
Ubiquitin-conjugating enzyme E2 T (UniProt Q9NPD8), EC 2.3.2.23: 16 experimental structures on GenesisL1, 5 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9NPD8
- Protein
- Ubiquitin-conjugating enzyme E2 T
- EC
- 2.3.2.23
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 4 · 3 records with a druggable one
Structures
16 records of Q9NPD8 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YH2 | Ubiquitin-Conjugating Enzyme HSPC150 | x-ray diffraction | A | — | — |
| 1YH2 | Ubiquitin-conjugating enzyme HSPC150 | x-ray diffraction | A | — | — |
| 4CCG | Structure of an E2-E3 complex | x-ray diffraction | A, B | — | — |
| 4CCG | Structure of an E2-E3 complex | x-ray diffraction | A, B | — | — |
| 5NGZ | UBE2T in complex with fragment EM04 | x-ray diffraction | A | 2BG | — |
| 5OJJ | Crystal structure of the zn-bound ubiquitin-conjugating enzyme UBE2T | x-ray diffraction | A, B, C, D, E, F | ZN | — |
| 6R75 | Crystal structure of human Ube2T E54R mutant | x-ray diffraction | A | — | — |
| 6R75 | Crystal structure of human UBE2T E54R mutant | x-ray diffraction | A | — | — |
| 7KZR | Structure of the human Fanconi Anaemia Core-UBE2T-ID complex | electron microscopy | X | — | 1 (best 0.85) |
| 7KZS | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in open state | electron microscopy | X | — | 1 (best 0.82) |
| 7KZT | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state | electron microscopy | X | — | — |
| 7KZV | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in closed state | electron microscopy | X | — | 1 (best 0.86) |
| 8JVD | Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through… | x-ray diffraction | A | V2R | — |
| 8JVE | Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T… | x-ray diffraction | A | V6C | — |
| 8JVL | Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T… | x-ray diffraction | A | V5L | 1 (best 0.26) |
| Q9NPD8 | AlphaFold monomer V2.0 prediction for ubiquitin-conjugating enzyme E2 T (Q9NPD8) | — | — | — |
Ligands
Elsewhere
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