UniProt O15360
Fanconi anemia group A protein (O15360)
Fanconi anemia group A protein (UniProt O15360): 6 experimental structures and 1 predicted model on GenesisL1, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15360
- Protein
- Fanconi anemia group A protein
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 32 · 5 records with a druggable one
Structures
7 records of O15360 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7KZP | Structure of the human Fanconi anaemia Core complex | electron microscopy | A, S | — | 7 (best 0.81) |
| 7KZQ | Structure of the human Fanconi anaemia Core-ID complex | electron microscopy | A, S | — | 10 (best 0.85) |
| 7KZR | Structure of the human Fanconi Anaemia Core-UBE2T-ID complex | electron microscopy | A, S | — | 4 (best 0.86) |
| 7KZS | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in open state | electron microscopy | A, S | — | 4 (best 0.87) |
| 7KZT | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state | electron microscopy | A, S | — | — |
| 7KZV | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in closed state | electron microscopy | A, S | — | 7 (best 0.85) |
| O15360 | AlphaFold monomer V2.0 prediction for fanconi anemia group a protein (O15360) | predicted | A | — | — |
Experiment against prediction
- 7KZQ chain S against the predicted model O15360: TM-score 0.76, RMSD 5.56 Å
- 7KZP chain S against the predicted model O15360: TM-score 0.75, RMSD 5.52 Å
- 7KZR chain S against the predicted model O15360: TM-score 0.75, RMSD 5.51 Å
- 7KZS chain S against the predicted model O15360: TM-score 0.75, RMSD 5.74 Å
- 7KZV chain S against the predicted model O15360: TM-score 0.75, RMSD 5.84 Å
- 7KZT chain S against the predicted model O15360: TM-score 0.75, RMSD 5.96 Å
- 7KZV chain A against the predicted model O15360: TM-score 0.60, RMSD 2.69 Å
- 7KZR chain A against the predicted model O15360: TM-score 0.60, RMSD 3.12 Å
- 7KZS chain A against the predicted model O15360: TM-score 0.59, RMSD 2.72 Å
- 7KZQ chain A against the predicted model O15360: TM-score 0.59, RMSD 2.97 Å
Elsewhere
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