UniProt Q9BXW9
Fanconi anemia group D2 protein (Q9BXW9)
Fanconi anemia group D2 protein (UniProt Q9BXW9): 18 experimental structures and 1 predicted model on GenesisL1, 82 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BXW9
- Protein
- Fanconi anemia group D2 protein
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 82 · 11 records with a druggable one
Structures
19 records of Q9BXW9 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6VAA | Structure of the Fanconi Anemia ID complex bound to ICL DNA | electron microscopy | B | — | 13 (best 0.81) |
| 6VAA | Structure of the fanconi anemia id complex bound to icl DNA | electron microscopy | B | — | — |
| 6VAD | Fanconi Anemia ID complex | electron microscopy | B | — | 12 (best 0.80) |
| 6VAD | Fanconi anemia id complex | electron microscopy | B | — | — |
| 6VAE | Mono-ubiquitinated Fanconi Anemia ID complex bound to ICL DNA | electron microscopy | B | — | 10 (best 0.85) |
| 6VAE | Mono-ubiquitinated fanconi anemia id complex bound to icl DNA | electron microscopy | B | — | — |
| 6VAF | Structure of mono-ubiquitinated FANCD2 bound to non-ubiquitinated FANCI and to DNA | electron microscopy | B | — | — |
| 6VAF | Structure of mono-ubiquitinated FANCD2 bound to non-ubiquitinated fanci and to DNA | electron microscopy | B | — | — |
| 7AY1 | Cryo-EM structure of USP1-UAF1 bound to mono-ubiquitinated FANCD2, and FANCI | electron microscopy | B | — | 10 (best 0.69) |
| 7AY1 | Cryo-EM structure of USP1-UAF1 bound to mono-ubiquitinated FANCD2, and fanci | electron microscopy | B | — | — |
| 7KZQ | Structure of the human Fanconi anaemia Core-ID complex | electron microscopy | V | — | 1 (best 0.82) |
| 7KZR | Structure of the human Fanconi Anaemia Core-UBE2T-ID complex | electron microscopy | V | — | 2 (best 0.85) |
| 7KZS | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in open state | electron microscopy | V | — | 4 (best 0.82) |
| 7KZT | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state | electron microscopy | V | — | — |
| 7KZV | Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in closed state | electron microscopy | V | — | 2 (best 0.86) |
| 7ZF1 | Structure of ubiquitinated FANCI in complex with FANCD2 and double-stranded DNA | electron microscopy | B | — | 10 (best 0.86) |
| 8A9J | Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 without ML323… | electron microscopy | B | — | 9 (best 0.70) |
| 8A9K | Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 with ML323 (consensus… | electron microscopy | B | — | 9 (best 0.73) |
| Q9BXW9 | AlphaFold monomer V2.0 prediction for fanconi anemia group D2 protein (Q9BXW9) | predicted | A | — | — |
Experiment against prediction
- 8A9J chain B against the predicted model Q9BXW9: TM-score 0.86, RMSD 4.13 Å
- 8A9K chain B against the predicted model Q9BXW9: TM-score 0.86, RMSD 4.10 Å
- 6VAA chain B against the predicted model Q9BXW9: TM-score 0.85, RMSD 4.93 Å
- 6VAA chain B against the predicted model Q9BXW9: TM-score 0.85, RMSD 4.93 Å
- 6VAD chain B against the predicted model Q9BXW9: TM-score 0.84, RMSD 4.98 Å
- 6VAD chain B against the predicted model Q9BXW9: TM-score 0.84, RMSD 4.98 Å
- 7KZR chain V against the predicted model Q9BXW9: TM-score 0.83, RMSD 5.18 Å
- 7KZQ chain V against the predicted model Q9BXW9: TM-score 0.83, RMSD 5.12 Å
- 7AY1 chain B against the predicted model Q9BXW9: TM-score 0.82, RMSD 5.41 Å
- 7AY1 chain B against the predicted model Q9BXW9: TM-score 0.82, RMSD 5.41 Å
Elsewhere
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