MolNFT v2 · #180095 · protein
Lasmiditan-bound serotonin 1F (5-HT1F) receptor-Gi protein complex
7EXD: “Lasmiditan-bound serotonin 1F (5-HT1F) receptor-Gi protein complex”. Electron microscopy at 3.4, 1 ligand (05X). MolNFT v2 #180095 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7EXD
- Type
- protein
- Length
- 1,118 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.4
- Source
- Escherichia coli; Homo sapiens; Mus musculus
- UniProt
- P63096, P62873, P59768, P0ABE7, P30939
- Ligands
- 05X
Structure
electron microscopy · resolution 3.4 · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 219 | — | P63096 |
| B | — | protein | 337 | — | P62873 |
| G | — | protein | 58 | — | P59768 |
| E | — | protein | 232 | — | — |
| R | — | protein | 272 | — | P0ABE7, P30939 |
Ligands and binding sites
- 05X · 2,4,6-tris(fluoranyl)-N-[6-(1-methylpiperidin-4-yl) carbonylpyridin-2-yl]benzamide · ligand · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7EXD · Lasmiditan-bound serotonin 1F (5-HT1F) receptor-gi protein complex · the same entry in another collection · chain R against R, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P30939 · AlphaFold monomer V2.0 prediction for 5-hydroxytryptamine receptor 1F (P30939) · a predicted model of the same protein · chain R against A, TM-score 0.92
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.92
- P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.81
- P0ABE7 · AlphaFold monomer V2.0 prediction for soluble cytochrome B562 (P0ABE7) · a predicted model of the same protein · chain R against A, TM-score 0.28
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63096
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt P0ABE7
- Every structure of UniProt P30939
- Elsewhere: RCSB PDB 7EXD · PDBe 7EXD · UniProt P63096 · UniProt P62873 · UniProt P59768 · UniProt P0ABE7 · UniProt P30939
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