MolNFT v2 · #157796 · protein
XFEL crystal structure of human melatonin receptor MT2 in complex with ramelteon
6ME9: “XFEL crystal structure of human melatonin receptor MT2 in complex with ramelteon”. X-ray diffraction at 3.3, 2 ligands (JEV, ZN). MolNFT v2 #157796 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6ME9
- Type
- protein
- Length
- 843 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.3
- Source
- Clostridium pasteurianum; Escherichia coli; Homo sapiens
- UniProt
- P0ABE7, P49286, P00268
- Ligands
- JEV, ZN
Structure
x-ray diffraction · resolution 3.3 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 448 | — | P0ABE7, P49286, P00268 |
| B | — | protein | 395 | — | P0ABE7, P49286, P00268 |
Ligands and binding sites
- JEV · N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6ME9 · Xfel crystal structure of human melatonin receptor MT2 in complex with ramelteon · the same entry in another collection · chain A against A, TM-score 1.00
- P49286 · AlphaFold monomer V2.0 prediction for melatonin receptor type 1B (P49286) · a predicted model of the same protein · chain B against A, TM-score 0.71
- P0ABE7 · AlphaFold monomer V2.0 prediction for soluble cytochrome B562 (P0ABE7) · a predicted model of the same protein · chain B against A, TM-score 0.26
- P00268 · AlphaFold monomer V2.0 prediction for rubredoxin (P00268) · a predicted model of the same protein · chain A against A, TM-score 0.12
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0ABE7
- Every structure of UniProt P49286
- Every structure of UniProt P00268
- Elsewhere: RCSB PDB 6ME9 · PDBe 6ME9 · UniProt P0ABE7 · UniProt P49286 · UniProt P00268
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.