MolNFT v2 · #14346 · protein
Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
1M63: “Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of…”. X-ray diffraction at 2.8. MolNFT v2 #14346 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1M63
- Type
- protein
- Length
- 1,401 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.8
- Source
- HOMO SAPIENS; SYNTHETIC CONSTRUCT
- UniProt
- Q08209, P63098, P62937
Structure
x-ray diffraction · resolution 2.8 · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 372 | — | Q08209 |
| B | — | protein | 158 | — | P63098 |
| C, G | — | protein | 165 | — | P62937 |
| D, H | — | protein | 11 | — | — |
| E | — | protein | 359 | — | Q08209 |
| F | — | protein | 160 | — | P63098 |
Compared structures
- 1M63 · Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct… · the same entry in another collection · chain H against H, TM-score 1.00
- Q08209 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase 2B catalytic… · a predicted model of the same protein · chain E against A, TM-score 0.96
- P63098 · AlphaFold monomer V2.0 prediction for calcineurin subunit B type 1 (P63098) · a predicted model of the same protein · chain F against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08209
- Every structure of UniProt P63098
- Every structure of UniProt P62937
- Elsewhere: RCSB PDB 1M63 · PDBe 1M63 · UniProt Q08209 · UniProt P63098 · UniProt P62937
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