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MolNFT v1 · #14337 · protein

Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes

1M63: “Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of…”. X-ray diffraction. MolNFT v1 #14337 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
1M63
Type
protein
Length
1,401 residues
Chains
8
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q08209, P63098, P62937

Structure

x-ray diffraction · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein372—Q08209
B—protein158—P63098
C, G—protein165—P62937
D, H—protein11——
E—protein359—Q08209
F—protein160—P63098

Compared structures

  • 1M63 · Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct… · the same entry in another collection · chain H against H, TM-score 1.00
  • Q08209 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase 2B catalytic… · a predicted model of the same protein · chain E against A, TM-score 0.96
  • P63098 · AlphaFold monomer V2.0 prediction for calcineurin subunit B type 1 (P63098) · a predicted model of the same protein · chain F against A, TM-score 0.95

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