MolNFT v2 · #117075 · protein
Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated Galpha-q
5DO9: “Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated Galpha-q”. X-ray diffraction at 2.6, 3 ligands (GDP, ALF, MG). MolNFT v2 #117075 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5DO9
- Type
- protein
- Length
- 1,343 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.6
- Source
- Homo sapiens; Mus musculus
- UniProt
- P21279, P57771
- Ligands
- GDP, ALF, MG
Structure
x-ray diffraction · resolution 2.6 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | — | protein | 314 | — | P21279 |
| B, D, F | — | protein | 134 | — | P57771 |
| E | — | protein | 313 | — | P21279 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 3 copies · chains A, C, E
- ALF · Tetrafluoroaluminate ion · ligand · 3 copies · chains A, C, E
- MG · Magnesium ion · metal · 3 copies · chains A, C, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5DO9 · Structure of regulator of G protein signaling 8 (RGS8) in complex with ALF4-activated… · the same entry in another collection · chain F against F, TM-score 1.00
- P21279 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(Q) subunit… · a predicted model of the same protein · chain E against A, TM-score 0.98
- P57771 · AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 8 (P57771) · a predicted model of the same protein · chain B against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21279
- Every structure of UniProt P57771
- Elsewhere: RCSB PDB 5DO9 · PDBe 5DO9 · UniProt P21279 · UniProt P57771
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