UniProt P57771
Regulator of G-protein signaling 8 (P57771)
Regulator of G-protein signaling 8 (UniProt P57771): 6 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P57771
- Protein
- Regulator of G-protein signaling 8
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
7 records of P57771 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IHD | Crystal structure of Human Regulator of G-protein signaling 8, RGS8 | x-ray diffraction | A | — | — |
| 2IHD | Crystal structure of human regulator of G-protein signaling 8, RGS8 | x-ray diffraction | A | — | — |
| 2ODE | Crystal structure of the heterodimeric complex of human RGS8 and activated Gi alpha 3 | x-ray diffraction | B, D | — | — |
| 2ODE | Crystal structure of the heterodimeric complex of human RGS8 and activated gi alpha 3 | x-ray diffraction | B, D | — | — |
| 5DO9 | Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated Galpha-q | x-ray diffraction | B, D, F | — | — |
| 5DO9 | Structure of regulator of G protein signaling 8 (RGS8) in complex with ALF4-activated galpha-Q | x-ray diffraction | B, D, F | — | — |
| P57771 | AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 8 (P57771) | predicted | A | — | 1 (best 0.54) |
Experiment against prediction
- 2ODE chain D against the predicted model P57771: TM-score 0.99, RMSD 0.29 Å
- 2ODE chain D against the predicted model P57771: TM-score 0.99, RMSD 0.29 Å
- 2ODE chain B against the predicted model P57771: TM-score 0.99, RMSD 0.47 Å
- 2ODE chain B against the predicted model P57771: TM-score 0.99, RMSD 0.47 Å
- 2IHD chain A against the predicted model P57771: TM-score 0.99, RMSD 0.49 Å
- 2IHD chain A against the predicted model P57771: TM-score 0.99, RMSD 0.49 Å
- 5DO9 chain B against the predicted model P57771: TM-score 0.93, RMSD 1.25 Å
- 5DO9 chain B against the predicted model P57771: TM-score 0.93, RMSD 1.25 Å
Elsewhere
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