MolNFT v1 · #341762 · protein
AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 8 (P57771)
P57771: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 8 (P57771)”. 1 pocket (best druggability 0.54). MolNFT v1 #341762 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P57771
- Type
- protein
- Length
- 180 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- Regulator of G-protein signaling 8
- UniProt
- P57771
- Pockets
- 1 · best druggability 0.54
Structure
1 distinct chain · 57% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of G-protein signaling 8 | protein | 180 | 57% helix, 0% strand | P57771 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 137 | 0.54 | 0.81 | 24 | empty |
Compared structures
- 2ODE · Crystal structure of the heterodimeric complex of human RGS8 and activated gi alpha 3 · an experimental structure of the same protein · chain A against B, TM-score 0.72
- 2ODE · Crystal structure of the heterodimeric complex of human RGS8 and activated Gi alpha 3 · an experimental structure of the same protein · chain A against B, TM-score 0.72
- 5DO9 · Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated… · an experimental structure of the same protein · chain A against B, TM-score 0.70
- 5DO9 · Structure of regulator of G protein signaling 8 (RGS8) in complex with ALF4-activated… · an experimental structure of the same protein · chain A against B, TM-score 0.70
- 2IHD · Crystal structure of Human Regulator of G-protein signaling 8, RGS8 · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 2IHD · Crystal structure of human regulator of G-protein signaling 8, RGS8 · an experimental structure of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P57771
- Elsewhere: UniProt P57771 · AlphaFold DB P57771
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