MolNFT v1 · #68295 · protein
SEC13 with NUP145C (AA109-179) insertion blade
3JRP · Fusion protein of protein transport protein SEC13 and…: “SEC13 with NUP145C (AA109-179) insertion blade”. X-ray diffraction, 4 pockets (best druggability 0.80). MolNFT v1 #68295 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 3JRP
- Type
- protein
- Length
- 335 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fusion protein of protein transport protein SEC13 and nucleoporin NUP145
- UniProt
- Q04491, P49687
- Pockets
- 4 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 4% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fusion protein of protein transport protein SEC13 and nucleoporin NUP145 | protein | 335 | 4% helix, 52% strand | Q04491, P49687 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 522 | 0.80 | 0.87 | 49 | empty |
| 2 | 63 | 0.35 | 0.77 | 21 | empty |
| 3 | 78 | 0.34 | 0.75 | 14 | empty |
| 4 | 52 | 0.32 | 0.78 | 17 | empty |
Compared structures
- 3JRP · SEC13 with NUP145C (AA109-179) insertion blade · the same entry in another collection · chain A against A, TM-score 1.00
- Q04491 · AlphaFold monomer V2.0 prediction for protein transport protein SEC13 (Q04491) · a predicted model of the same protein · chain A against A, TM-score 0.82
- P49687 · AlphaFold monomer V2.0 prediction for nucleoporin NUP145 (P49687) · a predicted model of the same protein · chain A against A, TM-score 0.28
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q04491
- Every structure of UniProt P49687
- Elsewhere: RCSB PDB 3JRP · PDBe 3JRP · UniProt Q04491 · UniProt P49687
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