MolNFT v1 · #271658 · protein
AlphaFold monomer V2.0 prediction for nucleoporin NUP145 (P49687)
P49687: “AlphaFold monomer V2.0 prediction for nucleoporin NUP145 (P49687)”. 6 pockets (best druggability 0.53). MolNFT v1 #271658 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49687
- Type
- protein
- Length
- 1,317 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7A4835E1d5C827cCdBb787F0BA47F7B72797C5bb
- Molecule
- Nucleoporin NUP145
- UniProt
- P49687
- Pockets
- 6 · best druggability 0.53
Structure
1 distinct chain · 35% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoporin NUP145 | protein | 1317 | 35% helix, 5% strand | P49687 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 114 | 0.53 | 0.82 | 16 | empty |
| 2 | 52 | 0.51 | 0.88 | 14 | empty |
| 3 | 67 | 0.34 | 0.76 | 18 | empty |
| 4 | 67 | 0.31 | 0.75 | 13 | empty |
| 5 | 67 | 0.30 | 0.74 | 14 | empty |
Compared structures
- 7N84 · Double nuclear outer ring from the isolated yeast npc · an experimental structure of the same protein · chain A against n, TM-score 0.40
- 4XMM · Structure of the yeast coat nucleoporin complex, space group C2 · an experimental structure of the same protein · chain A against B, TM-score 0.38
- 4XMM · Structure of the yeast coat nucleoporin complex, space group C2 · an experimental structure of the same protein · chain A against B, TM-score 0.38
- 4XMN · Structure of the yeast coat nucleoporin complex, space group P212121 · an experimental structure of the same protein · chain A against B, TM-score 0.38
- 4XMN · Structure of the yeast coat nucleoporin complex, space group P212121 · an experimental structure of the same protein · chain A against B, TM-score 0.38
- 3IKO · Crystal structure of the heterotrimeric Sec13-Nup145C-Nup84 nucleoporin complex · an experimental structure of the same protein · chain A against B, TM-score 0.33
- 3IKO · Crystal structure of the heterotrimeric SEC13-NUP145C-NUP84 nucleoporin complex · an experimental structure of the same protein · chain A against B, TM-score 0.33
- 3JRO · NUP84-NUP145C-SEC13 edge element of the npc lattice · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 3JRO · NUP84-NUP145C-SEC13 edge element of the NPC lattice · an experimental structure of the same protein · chain A against A, TM-score 0.33
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49687
- Elsewhere: UniProt P49687 · AlphaFold DB P49687
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