UniProt P49687
Nucleoporin NUP145 (P49687)
Nucleoporin NUP145 (UniProt P49687): 19 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P49687
- Protein
- Nucleoporin NUP145
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
20 records of P49687 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3BG0 | Architecture of a Coat for the Nuclear Pore Membrane | x-ray diffraction | B, C, F, G | — | — |
| 3BG0 | Architecture of a coat for the nuclear pore membrane | x-ray diffraction | B, C, F, G | — | — |
| 3BG1 | Architecture of a Coat for the Nuclear Pore Membrane | x-ray diffraction | B, C, F, G | — | — |
| 3BG1 | Architecture of a coat for the nuclear pore membrane | x-ray diffraction | B, C, F, G | — | — |
| 3IKO | Crystal structure of the heterotrimeric Sec13-Nup145C-Nup84 nucleoporin complex | x-ray diffraction | B, E, H | — | — |
| 3IKO | Crystal structure of the heterotrimeric SEC13-NUP145C-NUP84 nucleoporin complex | x-ray diffraction | B, E, H | — | — |
| 3JRO | NUP84-NUP145C-SEC13 edge element of the NPC lattice | x-ray diffraction | A | — | — |
| 3JRO | NUP84-NUP145C-SEC13 edge element of the npc lattice | x-ray diffraction | A | — | — |
| 3JRP | SEC13 with NUP145C (AA109-179) insertion blade | x-ray diffraction | A | — | — |
| 3JRP | SEC13 with NUP145C (AA109-179) insertion blade | x-ray diffraction | A | — | — |
| 3KEP | Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from… | x-ray diffraction | A, B | — | — |
| 3KEP | Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from… | x-ray diffraction | A, B | — | — |
| 3KES | Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from… | x-ray diffraction | A, B | — | — |
| 3KES | Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from… | x-ray diffraction | A, B | — | — |
| 4XMM | Structure of the yeast coat nucleoporin complex, space group C2 | x-ray diffraction | B | — | — |
| 4XMM | Structure of the yeast coat nucleoporin complex, space group C2 | x-ray diffraction | B | — | — |
| 4XMN | Structure of the yeast coat nucleoporin complex, space group P212121 | x-ray diffraction | B | — | — |
| 4XMN | Structure of the yeast coat nucleoporin complex, space group P212121 | x-ray diffraction | B | — | — |
| 7N84 | Double nuclear outer ring from the isolated yeast npc | electron microscopy | c, n | — | — |
| P49687 | AlphaFold monomer V2.0 prediction for nucleoporin NUP145 (P49687) | predicted | A | — | 6 (best 0.53) |
Experiment against prediction
- 3IKO chain B against the predicted model P49687: TM-score 0.99, RMSD 0.87 Å
- 3IKO chain B against the predicted model P49687: TM-score 0.99, RMSD 0.87 Å
- 3IKO chain H against the predicted model P49687: TM-score 0.99, RMSD 0.91 Å
- 3IKO chain H against the predicted model P49687: TM-score 0.99, RMSD 0.91 Å
- 3IKO chain E against the predicted model P49687: TM-score 0.98, RMSD 0.95 Å
- 3IKO chain E against the predicted model P49687: TM-score 0.98, RMSD 0.95 Å
- 3BG1 chain C against the predicted model P49687: TM-score 0.97, RMSD 1.39 Å
- 3BG1 chain C against the predicted model P49687: TM-score 0.97, RMSD 1.39 Å
- 4XMN chain B against the predicted model P49687: TM-score 0.97, RMSD 1.50 Å
- 4XMN chain B against the predicted model P49687: TM-score 0.97, RMSD 1.50 Å
Elsewhere
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