MolNFT v1 · #39942 · protein
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
2IAM: “Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR”. X-ray diffraction. MolNFT v1 #39942 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2IAM
- Type
- protein
- Length
- 813 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P01903, P04229, P60174, P01848, P01850
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 179 | — | P01903 |
| B | — | protein | 182 | — | P04229 |
| P | — | protein | 15 | — | P60174 |
| C | — | protein | 198 | — | P01848 |
| D | — | protein | 239 | — | P01850 |
Compared structures
- 2IAM · Structural basis for recognition of mutant self by a tumor-specific, MHC class… · the same entry in another collection · chain D against D, TM-score 1.00
- P01903 · AlphaFold monomer V2.0 prediction for HLA class II histocompatibility antigen, dr alpha… · a predicted model of the same protein · chain A against A, TM-score 0.96
- P01850 · AlphaFold monomer V2.0 prediction for T cell receptor beta constant 1 (P01850) · a predicted model of the same protein · chain D against A, TM-score 0.54
- P01848 · AlphaFold monomer V2.0 prediction for T cell receptor alpha chain constant (P01848) · a predicted model of the same protein · chain C against A, TM-score 0.44
- P60174 · AlphaFold monomer V2.0 prediction for triosephosphate isomerase (P60174) · a predicted model of the same protein · chain P against A, TM-score 0.22
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01903
- Every structure of UniProt P04229
- Every structure of UniProt P60174
- Every structure of UniProt P01848
- Every structure of UniProt P01850
- Elsewhere: RCSB PDB 2IAM · PDBe 2IAM · UniProt P01903 · UniProt P04229 · UniProt P60174 · UniProt P01848 · UniProt P01850
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