UniProt P01848
Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant (P01848)
Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant…
- UniProt
- P01848
- Protein
- Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta…
- Experimental structures
- 50
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 4 records with a druggable one
Structures
51 records of P01848 in the MolNFT archive: 50 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KGC | Immune Receptor | x-ray diffraction | D | — | — |
| 1KGC | Immune receptor | x-ray diffraction | D | — | — |
| 1MI5 | The crystal structure of LC13 TcR in complex with HLAB8-EBV peptide complex | x-ray diffraction | D | — | — |
| 1MI5 | The crystal structure of LC13 TCR in complex with HLAB8-EBV peptide complex | x-ray diffraction | D | — | — |
| 1QRN | Crystal structure of human A6 TCR complexed with HLA-A2 bound to altered HTLV-1 tax peptide P6A | x-ray diffraction | D | — | — |
| 1QRN | Crystal structure of human A6 TCR complexed with HLA-A2 bound to altered HTLV-1 tax peptide P6A | x-ray diffraction | D | — | — |
| 1ZGL | Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a | x-ray diffraction | M, Q, S, U | — | — |
| 1ZGL | Crystal structure of 3A6 TCR bound to MBP/HLA-DR2A | x-ray diffraction | M, Q, S, U | — | — |
| 2BNU | Structural and kinetic basis for heightened immunogenicity of T cell vaccines | x-ray diffraction | A, B | — | — |
| 2BNU | Structural and kinetic basis for heightened immunogenicity of T cell vaccines | x-ray diffraction | A, B | — | — |
| 2ESV | Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex | x-ray diffraction | D | — | — |
| 2ESV | Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex | x-ray diffraction | D | — | — |
| 2IAL | Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | x-ray diffraction | A, C | — | — |
| 2IAL | Structural basis for recognition of mutant self by a tumor- specific, MHC class II-restricted TCR | x-ray diffraction | A, C | — | — |
| 2IAM | Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | x-ray diffraction | C | — | — |
| 2IAM | Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | x-ray diffraction | C | — | — |
| 2IAN | Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | x-ray diffraction | D, I, N, S | — | — |
| 2IAN | Structural basis for recognition of mutant self by a tumor- specific, MHC class II-restricted TCR | x-ray diffraction | D, I, N, S | — | — |
| 2XN9 | Crystal structure of the ternary complex between human T cell receptor, staphylococcal enterotoxin… | x-ray diffraction | A | — | — |
| 2XN9 | Crystal structure of the ternary complex between human T cell receptor, staphylococcal enterotoxin… | x-ray diffraction | A | — | — |
| 2XNA | Crystal structure of the complex between human T cell receptor and staphylococcal enterotoxin | x-ray diffraction | A | — | — |
| 2XNA | Crystal structure of the complex between human T cell receptor and staphylococcal enterotoxin | x-ray diffraction | A | — | — |
| 3O6F | Crystal structure of a human autoimmune TCR MS2-3C8 bound to MHC class II self-ligand MBP/HLA-DR4 | x-ray diffraction | C, G | — | — |
| 3O6F | Crystal structure of a human autoimmune TCR MS2-3C8 bound to MHC class II self-ligand MBP/HLA-DR4 | x-ray diffraction | C, G | — | — |
| 3O8X | Recognition of Glycolipid Antigen by iNKT Cell TCR | x-ray diffraction | C | — | — |
| 3O8X | Recognition of glycolipid antigen by inkt cell TCR | x-ray diffraction | C | GSL | 5 (best 0.87) |
| 3O9W | Recognition of a Glycolipid Antigen by the iNKT Cell TCR | x-ray diffraction | C | — | — |
| 3O9W | Recognition of a glycolipid antigen by the inkt cell TCR | x-ray diffraction | C | — | — |
| 4UDT | T cell receptor (TRAV22,TRBV7-9) structure | x-ray diffraction | A | — | — |
| 4UDT | T cell receptor (TRAV22,TRBV7-9) structure | x-ray diffraction | A | — | — |
| 4UDU | Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor | x-ray diffraction | A | — | — |
| 4UDU | Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor | x-ray diffraction | A | — | — |
| 4ZDH | Crystal structure of JKA6 TCR | x-ray diffraction | A | — | — |
| 4ZDH | Crystal structure of JKA6 TCR | x-ray diffraction | A | — | — |
| 5BRZ | Mage-A3 reactive TCR in complex with mage-A3 in HLA-A1 | x-ray diffraction | D | — | — |
| 5BS0 | Mage-A3 reactive TCR in complex with titin epitope in HLA-A1 | x-ray diffraction | D | — | — |
| 6DKP | The complex among DMF5(ALPHA-D26Y, alpha-Y50A,BETA-L98W) TCR, human class I MHC HLA-A2 and… | x-ray diffraction | D | — | — |
| 6JXR | Structure of human T cell receptor-CD3 complex | electron microscopy | m | — | — |
| 6JXR | Structure of human T cell receptor-CD3 complex | electron microscopy | m | — | — |
| 7FJD | Cryo-EM structure of a membrane PROTEIN(WT) | electron microscopy | m | — | — |
| 7FJE | Cryo-EM structure of a membrane PROTEIN(LL) | electron microscopy | m | — | — |
| 7FJF | Cryo-EM structure of a membrane PROTEIN(CS) | electron microscopy | m | C3S | — |
| 7NDT | UL40:01 TCR in complex with HLA-E with a non-natural amino acid | x-ray diffraction | DDD, III | — | — |
| 7RYL | T cell receptor CO3 | x-ray diffraction | D | SO4 | — |
| 7RYM | CD1A-endo-gdtcr complex | x-ray diffraction | D | — | — |
| 7RYN | CD1A-sulfatide-gdtcr complex | x-ray diffraction | D | — | — |
| 7RYO | CD1a-dideoxymycobactin-gdTCR complex | x-ray diffraction | D | SO4 | 6 (best 0.74) |
| 7RYO | CD1A-dideoxymycobactin-gdtcr complex | x-ray diffraction | D | SO4 | — |
| 7T2C | Crystal structure of the B5 TCR in complex with HLA-DP4-Ply | x-ray diffraction | D | — | 7 (best 0.73) |
| 8WYI | T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC | electron microscopy | m | — | 4 (best 0.82) |
| P01848 | AlphaFold monomer V2.0 prediction for T cell receptor alpha chain constant (P01848) | predicted | A | — | 1 (best 0.31) |
Ligands
Experiment against prediction
- 8WYI chain m against the predicted model P01848: TM-score 0.83, RMSD 1.66 Å
- 8WYI chain m against the predicted model B7Z8K6: TM-score 0.77, RMSD 1.71 Å
- 2BNU chain B against the predicted model P01850: TM-score 0.53, RMSD 0.65 Å
- 2BNU chain B against the predicted model P01850: TM-score 0.53, RMSD 0.65 Å
- 4ZDH chain A against the predicted model P01848: TM-score 0.44, RMSD 0.91 Å
- 4ZDH chain A against the predicted model P01848: TM-score 0.44, RMSD 0.91 Å
- 4UDT chain A against the predicted model P01848: TM-score 0.44, RMSD 0.74 Å
- 4UDT chain A against the predicted model P01848: TM-score 0.44, RMSD 0.74 Å
- 2IAM chain C against the predicted model P01848: TM-score 0.44, RMSD 0.58 Å
- 2IAM chain C against the predicted model P01848: TM-score 0.44, RMSD 0.58 Å
Elsewhere
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