UniProt P01903
HLA class II histocompatibility antigen, DR alpha chain (P01903)
HLA class II histocompatibility antigen, DR alpha chain (UniProt P01903): 199 experimental structures and 1 predicted model on GenesisL1, 8 ligands bound, 41 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P01903
- Protein
- HLA class II histocompatibility antigen, DR alpha chain
- Experimental structures
- 199
- Predicted models
- 1
- Ligands
- 8
- Pockets
- 41 · 4 records with a druggable one
Structures
200 records of P01903 in the MolNFT archive: 199 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A6A | The structure of an intermediate in class II MHC maturation: clip bound to HLA-DR3 | x-ray diffraction | A | — | — |
| 1A6A | The structure of an intermediate in class II MHC maturation: clip bound to HLA-DR3 | x-ray diffraction | A | — | — |
| 1AQD | HLA-DR1 (dra, DRB1 0101) human class II histocompatibility protein (extracellular domain) complexed… | x-ray diffraction | A, D, G, J | — | — |
| 1AQD | HLA-DR1 (dra, DRB1 0101) human class II histocompatibility protein (extracellular domain) complexed… | x-ray diffraction | A, D, G, J | — | — |
| 1BX2 | Crystal structure of HLA-DR2 (DRA*0101,DRB1*1501) complexed with a peptide from human myelin basic… | x-ray diffraction | A, D | — | — |
| 1BX2 | Crystal structure of HLA-DR2 (DRA*0101,DRB1*1501) complexed with a peptide from human myelin basic… | x-ray diffraction | A, D | — | — |
| 1D5M | X-ray crystal structure of HLA-DR4 complexed with peptide and seb | x-ray diffraction | A | — | — |
| 1D5M | X-ray crystal structure of HLA-DR4 complexed with peptide and seb | x-ray diffraction | A | — | — |
| 1D5X | X-ray crystal structure of HLA-DR4 complexed with dipeptide mimetic and seb | x-ray diffraction | A | — | — |
| 1D5X | X-ray crystal structure of HLA-DR4 complexed with dipeptide mimetic and seb | x-ray diffraction | A | — | — |
| 1D5Z | X-ray crystal structure of HLA-DR4 complexed with peptidomimetic and seb | x-ray diffraction | A | — | — |
| 1D5Z | X-ray crystal structure of HLA-DR4 complexed with peptidomimetic and seb | x-ray diffraction | A | — | — |
| 1D6E | Crystal structure of HLA-DR4 complex with peptidomimetic and seb | x-ray diffraction | A | — | — |
| 1D6E | Crystal structure of HLA-DR4 complex with peptidomimetic and seb | x-ray diffraction | A | — | — |
| 1DLH | Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus… | x-ray diffraction | A, D | — | — |
| 1DLH | Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus… | x-ray diffraction | A, D | — | — |
| 1FV1 | Structural basis for the binding of an immunodominant peptide from myelin basic protein in… | x-ray diffraction | A, D | — | — |
| 1FV1 | Structural basis for the binding of an immunodominant peptide from myelin basic protein in… | x-ray diffraction | A, D | — | — |
| 1FYT | Crystal structure of a complex of a human ALPHA/BETA-T cell receptor, influenza ha antigen peptide… | x-ray diffraction | A | — | — |
| 1FYT | Crystal structure of a complex of a human ALPHA/BETA-T cell receptor, influenza ha antigen peptide… | x-ray diffraction | A | — | — |
| 1H15 | X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus… | x-ray diffraction | A, D | — | — |
| 1H15 | X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from epstein barr virus… | x-ray diffraction | A, D | — | — |
| 1HQR | Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II | x-ray diffraction | A | — | — |
| 1HQR | Crystal structure of a superantigen bound to the high- affinity, zinc-dependent site on MHC class II | x-ray diffraction | A | — | — |
| 1HXY | Crystal structure of staphylococcal enterotoxin H in complex with human MHC class II | x-ray diffraction | A | — | — |
| 1HXY | Crystal structure of staphylococcal enterotoxin H in complex with human MHC class II | x-ray diffraction | A | — | — |
| 1J8H | Crystal Structure of a Complex of a Human alpha/beta-T cell Receptor, Influenza HA Antigen Peptide… | x-ray diffraction | A | — | — |
| 1J8H | Crystal structure of a complex of a human ALPHA/BETA-T cell receptor, influenza ha antigen peptide… | x-ray diffraction | A | — | — |
| 1JWM | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the… | x-ray diffraction | A | — | — |
| 1JWM | Crystal structure of the complex of the MHC class II molecule HLA-DR1(HA peptide 306-318) with the… | x-ray diffraction | A | — | — |
| 1JWS | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the… | x-ray diffraction | A | — | — |
| 1JWS | Crystal structure of the complex of the MHC class II molecule HLA-DR1 (ha peptide 306-318) with the… | x-ray diffraction | A | — | — |
| 1JWU | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the… | x-ray diffraction | A | — | — |
| 1JWU | Crystal structure of the complex of the MHC class II molecule HLA-DR1 (ha peptide 306-318) with the… | x-ray diffraction | A | — | — |
| 1KG0 | Structure of the Epstein-Barr Virus gp42 Protein Bound to the MHC class II Receptor HLA-DR1 | x-ray diffraction | A | — | — |
| 1KG0 | Structure of the epstein-barr virus GP42 protein bound to the MHC class II receptor HLA-DR1 | x-ray diffraction | A | — | — |
| 1KLG | Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal… | x-ray diffraction | A | — | — |
| 1KLG | Crystal structure of HLA-DR1/TPI(23-37, THR28-->ile mutant) complexed with staphylococcal… | x-ray diffraction | A | — | — |
| 1KLU | Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2… | x-ray diffraction | A | — | — |
| 1KLU | Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2… | x-ray diffraction | A | — | — |
| 1LO5 | Crystal structure of the D227A variant of Staphylococcal enterotoxin A in complex with human MHC… | x-ray diffraction | A | — | — |
| 1LO5 | Crystal structure of the D227A variant of staphylococcal enterotoxin a in complex with human MHC… | x-ray diffraction | A | — | — |
| 1PYW | Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus… | x-ray diffraction | A | — | — |
| 1PYW | Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus… | x-ray diffraction | A | — | — |
| 1R5I | Crystal structure of the MAM-MHC complex | x-ray diffraction | A, E | — | — |
| 1R5I | Crystal structure of the mam-MHC complex | x-ray diffraction | A, E | — | — |
| 1SEB | Complex of the human MHC class II glycoprotein HLA-DR1 and the bacterial superantigen seb | x-ray diffraction | A, E | — | — |
| 1SEB | Complex of the human MHC class II glycoprotein HLA-DR1 and the bacterial superantigen seb | x-ray diffraction | A, E | — | — |
| 1SJE | HLA-DR1 complexed with a 16 residue HIV capsid peptide bound in a hairpin conformation | x-ray diffraction | A | — | — |
| 1SJE | HLA-DR1 complexed with a 16 residue HIV capsid peptide bound in a hairpin conformation | x-ray diffraction | A | — | — |
| 1SJH | HLA-DR1 complexed with a 13 residue HIV capsid peptide | x-ray diffraction | A | — | — |
| 1SJH | HLA-DR1 complexed with a 13 residue HIV capsid peptide | x-ray diffraction | A | — | — |
| 1T5W | HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) | x-ray diffraction | A, D | — | — |
| 1T5W | HLA-DR1 in complex with a synthetic peptide (aaysdqatplllspr) | x-ray diffraction | A, D | — | — |
| 1T5X | HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) and the superantigen SEC3-3B2 | x-ray diffraction | A | — | — |
| 1T5X | HLA-DR1 in complex with a synthetic peptide (aaysdqatplllspr) and the superantigen SEC3-3B2 | x-ray diffraction | A | — | — |
| 1YMM | TCR/HLA-DR2b/MBP-peptide complex | x-ray diffraction | A | — | — |
| 1YMM | TCR/HLA-DR2B/MBP-peptide complex | x-ray diffraction | A | — | — |
| 1ZGL | Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a | x-ray diffraction | A, D, G, J | — | — |
| 1ZGL | Crystal structure of 3A6 TCR bound to MBP/HLA-DR2A | x-ray diffraction | A, D, G, J | — | — |
140 records more on the page itself.
Ligands
Experiment against prediction
- 6ATZ chain A against the predicted model P01903: TM-score 0.97, RMSD 0.83 Å
- 6ATZ chain A against the predicted model P01903: TM-score 0.97, RMSD 0.83 Å
- 6CQN chain A against the predicted model P01903: TM-score 0.97, RMSD 0.87 Å
- 6CQL chain A against the predicted model P01903: TM-score 0.97, RMSD 0.87 Å
- 6CQL chain A against the predicted model P01903: TM-score 0.97, RMSD 0.87 Å
- 6ATZ chain C against the predicted model P01903: TM-score 0.97, RMSD 0.87 Å
- 6ATZ chain C against the predicted model P01903: TM-score 0.97, RMSD 0.87 Å
- 4Y19 chain A against the predicted model P01903: TM-score 0.97, RMSD 0.90 Å
- 4Y19 chain A against the predicted model P01903: TM-score 0.97, RMSD 0.90 Å
- 3PGD chain A against the predicted model P01903: TM-score 0.97, RMSD 0.92 Å
Elsewhere
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